Tumour resistance in induced pluripotent stem cells derived from naked mole-rats

NATURE COMMUNICATIONS Volume 7 published_at 2016-05
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Title
Tumour resistance in induced pluripotent stem cells derived from naked mole-rats
Creator
Miyawaki Shingo
Kawamura Yoshimi
Oiwa Yuki
Shimizu Atsushi
Hachiya Tsuyoshi
Bono Hidemasa
Koya Ikuko
Okada Yohei
Kimura Tokuhiro
Tsuchiya Yoshihiro
Suzuki Sadafumi
Onishi Nobuyuki
Kuzumaki Naoko
Narita Minoru
Ikeda Eiji
Okanoya Kazuo
Seino Ken-ichiro
Saya Hideyuki
Okano Hideyuki
Miura Kyoko
Source Title
NATURE COMMUNICATIONS
Volume 7
Journal Identifire
ISSN 2041-1723
Language
eng
Resource Type journal article
Publisher
NATURE PUBLISHING GROUP
Date of Issued 2016-05
Access Rights metadata only access
Relation
[DOI] 10.1038/ncomms11471
[PMID] 27161380
Remark We thank Drs D. Sipp for proofreading the manuscript; J. Kohyama, A. Takaoka and professors at the Institute for Genetic Medicine Hokkaido University for their administrative support and scientific discussion; N. Arai, C. Fukaya, Y. Tanabe and Y. Fujimura for help with animal maintenance; S. Osuka and all members of the H.O. and K.M. laboratories for technical assistance and scientific discussion; S. Yamanaka, K. Okita and K. Takahashi for 20D17-, 38C2 Nanog-EGFP Ms-iPSCs and 201B7 human-iPSCs; K. Niibe for N3E6 Ms-iPSCs; M. Ikawa and M. Okabe for EGR-G101 ESCs; H. Miyoshi for lentiviral vectors; T. Kitamura for PLAT-E and pMXs retroviral vectors; J. Miyazaki for pCAGGS-hLIF vectors; H. Naka-Kaneda for pCSII-EF-RfA-TK-hyg vector. This work was supported in part by PRESTO of the Japan Science and Technology Agency to K. M.; Grants-in-Aid for Scientific Research from the Japanese Society for the Promotion of Science from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) to K. M. and Y. K.; Grant-in-Aid for Scientific Research on Innovative Areas 'Oxygen Biology: a new criterion for integrated understanding of life' from the MEXT to K. M.; and the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program) to H.O. K. M. was supported by the Takeda Science Foundation, Mitsubishi Foundation, Japan Foundation For Aging And Health, Sekisui Chemical Innovations Inspired by Nature Research Support Program, Astellas Foundation for Research on Metabolic Disorders and Mochida Memorial Foundation for Medical and Pharmaceutical Research. K.M. and S.M. were Research Fellows of the Japanese Society for the Promotion of Science.