Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo

NATURE COMMUNICATIONS Volume 8 published_at 2017-02-6
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Title
Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo
Creator
Ozaki Taro
Yamashita Kona
Goto Yuki
Shimomura Morito
Asamizu Shumpei
Sugai Yoshinori
Ikeda Haruo
Suga Hiroaki
Onaka Hiroyasu
Source Title
NATURE COMMUNICATIONS
Volume 8
Journal Identifire
ISSN 2041-1723
Language
eng
Resource Type journal article
Publisher
NATURE PUBLISHING GROUP
Date of Issued 2017-02-6
Access Rights metadata only access
Relation
[DOI] 10.1038/ncomms14207
[PMID] 28165449
Remark We appreciate the assistance provided by Mizuho Nakaho and Yukari Kurokawa at Toyama Prefectural University, Hisashi Okamoto at The University of Tokyo for experiments, Yasuharu Kato at The University of Tokyo for technical supports in the in vitro experiments and Dr Joseph Rogers at The University of Tokyo for proof-reading. We also appreciate the LC-MS analysis support by Dr Mamoru Komatsu and Dr Kiyoko T.Miyamoto at Kitasato University, and Dr Naoya Oku at Toyama Prefectural University. This research was supported in part by a grant-in-aid from IFO, Institute for Fermentation, Osaka (to H.O., S.A. and T.O.), JSPS KAKENHI grant-in-aid for Young Scientists B (no. 26850043 to T.O. and no. 26850044 to S.A.), JSPS KAKENHI grant-in-aid for Challenging Exploratory Research (15K12739 to Y.G.), JST CREST of Molecular Technologies to H.S, JSPS KAKENHI (no. 25108707 to H.O.) and JSPS KAKENHI for Scientific Research on Innovative Areas (no. JP16H06444 to H.S, Y.G. and H.O.).