Title |
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels
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Creator |
Spracklen Cassandra N.
Chen Peng
Kim Young Jin
Wang Xu
Cai Hui
Li Shengxu
Long Jirong
Wu Ying
Wang Ya Xing
Takeuchi Fumihiko
Wu Jer-Yuarn
Jung Keum-Ji
Hu Cheng
Akiyama Koichi
Zhang Yonghong
Moon Sanghoon
Johnson Todd A.
Li Huaixing
Dorajoo Rajkumar
He Meian
Cannon Maren E.
Roman Tamara S.
Salfati Elias
Lin Keng-Hung
Guo Xiuqing
Sheu Wayne H. H.
Absher Devin
Adair Linda S.
Assimes Themistocles L.
Aung Tin
Cai Qiuyin
Chang Li-Ching
Chen Chien-Hsiun
Chien Li-Hsin
Chuang Lee-Ming
Chuang Shu-Chun
Du Shufa
Fan Qiao
Fann Cathy S. J.
Feranil Alan B.
Friedlander Yechiel
Gordon-Larsen Penny
Gu Dongfeng
Gui Lixuan
Guo Zhirong
Heng Chew-Kiat
Hixson James
Hou Xuhong
Hsiung Chao Agnes
Hu Yao
Hwang Mi Yeong
Hwu Chii-Min
Isono Masato
Juang Jyh-Ming Jimmy
Khor Chiea-Chuen
Kim Yun Kyoung
Koh Woon-Puay
Kubo Michiaki
Lee I-Te
Lee Sun-Ju
Lee Wen-Jane
Liang Kae-Woei
Lim Blanche
Lim Sing-Hui
Liu Jianjun
Pan Wen-Harn
Peng Hao
Quertermous Thomas
Sabanayagam Charumathi
Sandow Kevin
Shi Jinxiu
Sun Liang
Tan Pok Chien
Tan Shu-Pei
Taylor Kent D.
Teo Yik-Ying
Toh Sue-Anne
Tsunoda Tatsuhiko
van Dam Rob M.
Wang Aili
Wang Feijie
Wang Jie
Wei Wen Bin
Xiang Yong-Bing
Yao Jie
Yuan Jian-Min
Zhang Rong
Zhao Wanting
Chen Yii-Der Ida
Rich Stephen S.
Rotter Jerome I.
Wang Tzung-Dau
Wu Tangchun
Lin Xu
Han Bok-Ghee
Tanaka Toshihiro
Cho Yoon Shin
Katsuya Tomohiro
Jia Weiping
Jee Sun-Ha
Chen Yuan-Tsong
Kato Norihiro
Jonas Jost B.
Cheng Ching-Yu
Shu Xiao-Ou
He Jiang
Zheng Wei
Wong Tien-Yin
Huang Wei
Kim Bong-Jo
Tai E-Shyong
Mohlke Karen L.
Sim Xueling
|
Source Title |
HUMAN MOLECULAR GENETICS
|
Volume | 26 |
Issue | 9 |
Start Page | 1770 |
End Page | 1784 |
Journal Identifire |
ISSN 0964-6906
EISSN 1460-2083
|
Language |
eng
|
Resource Type | journal article |
Publisher |
OXFORD UNIV PRESS
|
Date of Issued | 2017-05-1 |
Access Rights | metadata only access |
Relation |
[DOI] 10.1093/hmg/ddx062
[PMID] 28334899
|
Remark | The Beijing Eye Study (BES) was funded by National Natural Science Foundation of China (NSFC, No. 81170890 and 81570835). The CAGE Network Studies were supported by grants for the Core Research for Evolutional Science and Technology (CREST) from the Japan Science Technology Agency; the Program for Promotion of Fundamental Studies in Health Sciences, National Institute of Biomedical Innovation Organization (NIBIO); and the Grant of National Center for Global Health and Medicine (NCGM). The China Health and Nutrition Survey (CHNS) was supported by the China National Institute of Nutrition and Food Safety; the China Center for Disease Control; the National Institutes of Health (R01HD30880, R01HL108427, and R01DK104371); the Fogarty International Center of the National Institutes of Health; the China-Japan Friendship Hospital; the Chinese Ministry of Health; and the Carolina Population Center (R24 HD050924). The Cebu Longitudinal Health and Nutrition Survey (CLHNS) was supported by National Institutes of Health grants DK078150, TW005596 and HL085144; pilot funds from RR020649, ES010126, and DK056350; and the Office of Population Studies Foundation. The Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study was supported by research grants (U01HL072507, R01HL087263, and R01HL090682) from the National Heart, Lung, and Blood Institute, National Institutes of Health, and partially supported by the Collins C. Diboll Private Foundation, New Orleans, LA, USA. The Korean Association Resource (KARE) study was supported by grants from Korea Centers for Disease Control and Prevention (4845-301, 4851-302, 4851-307) and an intramural grant from the Korea National Institute of Health (2016-NI73001-00). The Korean-Cancer Prevention Study-II (KCPSII) was funded by a grant of the Korean Health Technology R& D Project, Ministry of Health & Welfare, Republic of Korea (HI14C2686). The Shanghai Breast Cancer Study (SBCS) was supported by grants from the US National Institutes of Health (R01CA124558, R01CA064277, and R01CA090899). The Singapore Chinese Eye Study (SCES), and Singapore Malay Eye Study (SiMES) are supported by the National Medical Research Council (NMRC), Singapore (grants 0796/2003, 1176/2008, 1149/2008, STaR/0003/2008, 1249/2010, CG/SERI/2010, CIRG/1371/2013, and CIRG/1417/2015), and Biomedical Research Council (BMRC), Singapore (08/1/35/19/550 and 09/1/35/19/616). The Singapore Prospective Study Program (SP2) was supported by the individual research grant and clinician scientist award schemes from the National Medical Research Council (NMRC) and the Biomedical Research Council (BMRC) of Singapore. The Shanghai Women's Health Study and Shanghai Men's Health Studies (SWMHS) were supported by grants from the US National Institutes of Health (R37CA070867, R01CA082729, UM1CA182910, UM1CA173640). GWAS were supported by R37CA070867, R01CA082729, R01CA124558, R01CA148667, R01CA122364, R01CA122756, and R01CA137013, as well as Ingram Professorship and Research Reward funds from the Vanderbilt University School of Medicine. Sample preparation and genotyping assays at Vanderbilt were conducted at the Survey and Biospecimen Shared Resources and Vanderbilt Microarray Shared Resource, which were supported in part by Vanderbilt-Ingram Cancer Center (P30CA068485). The Taiwan Super Control Study (TWSC) was supported by a grant from Academia Sinica, Taipei, Taiwan (IBMS 40-05-GMM). The Dongfeng-Tongji cohort study (DFTJ-cohort) was supported by the grant from the National Natural Science Foundation (grant NSFC-81230069 to T.; Wu, grant NSFC-81473051 and 81522040 to M. He). The Health Examinee (HEXA) was supported by grants from Korea Centers for Disease Control and Prevention (4845301, 4851-302, 4851-307) and an intramural grant from the Korea National Institute of Health (2016-NI73001-00). The CAGE Amagasaki Study was supported in part by grants from SENSHIN Medical Research Foundation. Health2 was supported by grants from Korea Centers for Disease Control and Prevention (4845-301, 4851-302, 4851-307) and an intramural grant from the Korea National Institute of Health (2016NI73001- 00). The Nutrition and Health of Aging Population in China (NHAPC) study was supported by the Major Project of the Ministry of Science and Technology of China (2016-YFC1304903), the National Natural Science Foundation of China (81471013, 30930081, 81321062, 81170734 and 81471013), and the Chinese Academy of Sciences (KJZD-EW-L14). The Singapore Chinese Health Study (SCHS) was supported by the National Institutes of Health, USA (RO1CA144034 and UM1CA182876), the nested casecontrol study of myocardial infarction by the Singapore National Medical Research Council (NMRC 1270/2010) and genotyping by the HUJ-CREATE Programme of the National Research Foundation, Singapore (Project Number 370062002). The Shanghai Diabetes Inpatient Database (SDIID) was supported by National Science Foundation of China (81322010). The work at Shanghai Jiao Tong University Affiliated Sixth People's Hospital for Shanghai Diabetes Inpatient Database (SDIID) and Shanghai Diabetes Study (SHDS) was supported by grants from National 973 Program (2011CB504001), NSFC (81322010 and 81170735), Shanghai Rising Star Program (12QH1401700), Shanghai Talent Development Grant (2012041), Excellent Young Medical Expert of Shanghai (XYQ2011041) and National Young Top Talent Support Program. The Suzhou Metabolic Syndrome Study (SMSS) was supported by The National Natural Science Foundation of China (81320108026), and is a Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions, China. The Multi-Ethnic Study of Atherosclerosis study (MESA) was supported by the MultiEthnic Study of Atherosclerosis (MESA) contracts N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169 and by grants UL1-TR-000040 and UL1-RR-025005 from NCRR. Funding for MESA SHARe genotyping was provided by NHLBI Contract N02-HL-6-4278. The provision of genotyping data was supported in part by the National Center for Advancing Translational Sciences, CTSI grant UL1TR001881, and the National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DRC) grant DK063491 to the Southern California Diabetes Endocrinology Research Center. The TaiChi consortium (TaiChi) study was supported by the National Health Research Institutes, Taiwan (PH-100-SP-01, BS-094-PP-01, PH-100-PP-03), the National Science Council, Taiwan (Grant Nos NSC 98-2314-B-075A-002-MY3, NSC 96-2314-B-002-151, NSC 96-2314-B-002-152, NSC 98-2314-B-002-122-MY2, NSC 100-2314-B-002-115, NSC 101-2325-002-078, 101-2314-B-075A-006-MY3), the National Taiwan University Hospital, Taiwan (NTUH 98-N1266, NTUH 100-N1775, NTUH 101-N2010, NTUH 101-N, VN101-04, NTUH 101-S1784).; The TaiChi-G study was supported by the National Health Research Institutes, Taiwan (PH-100-SP-01, BS-094-PP-01, PH-100-PP-03), the National Science Council, Taiwan (Grant Nos NSC 98-2314-B-075A-002-MY3, NSC 96-2314-B-002-151, NSC 96-2314-B-002-152, NSC 98-2314-B-002-122-MY2, NSC 100-2314-B-002-115, NSC 101-2325-002-078, 101-2314-B-075A-006-MY3), the National Taiwan University Hospital, Taiwan (NTUH 98-N1266, NTUH 100-N1775, NTUH 101-N2010, NTUH 101-N, VN101-04, NTUH 101-S1784). The Taiwan-US Diabetic Retinopathy (TUDR) study was supported by the National Eye Institute of the National Institutes of Health (EY014684 to J. I. R. and Y.-D.I.C.) and ARRA Supplement (EY014684-03S1, -04S1), the Eye Birth Defects Foundation Inc., the National Science Council, Taiwan (MOST 104-2314-B-075A-006 -MY3 to W.H.S., MOST 104-2314-B-075A-007 to I.T.L.) and the Taichung Veterans General Hospital, Taichung, Taiwan (TCVGH-HK1028001, TCVGH-HK1048002, TCVGH-HK1058001 to W.J.L., TCVGH-VHCY1058605 to K.H.L., TCVGH-VTA105T4-3 to I.T.L.). DNA handling and genotyping were supported in part by the National Center for Advancing Translational Sciences, CTSI grant UL1TR001881 and the National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DRC) grant DK063491 to the Southern California Diabetes Endocrinology Research Center. Cassandra N. Spracklen was supported by the American Heart Association Postdoctoral Fellowship (15POST24470131). Peng Chen was supported by Changbai Mountain Scholar Award Program of Jilin Province China, and National Recruitment Program for Young Professionals of the Thousand Talents Plan China. Shengxu Li was partly supported by grant 13SDG14650068 from American Heart Association. Maren E. Cannon was supported by National Institutes of Health F31 HL127984. Tamara S. Roman was supported by National Institutes of Health R01 DK072193. Ching-Yu Cheng was supported by an award from NMRC (CSA/033/2012). Yoon Shin Cho acknowledged support from the National Research Foundation of Korea (NRF) grant (NRF-2012M3A9D1054534). |