Title |
Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis
|
Creator |
Oba Daiju
Inoue Shin-ichi
Miyagawa-Tomita Sachiko
Nakashima Yasumi
Niihori Tetsuya
Matsubara Yoichi
Aoki Yoko
|
Source Title |
EBIOMEDICINE
|
Volume | 27 |
Start Page | 138 |
End Page | 150 |
Journal Identifire |
ISSN 2352-3964
|
Subjects |
Costello syndrome; Hras G12S; Mitochondrial fatty acid oxidation; Diet-induced obesity; Cancer metabolism; ERK
|
Language |
eng
|
Resource Type | journal article |
Publisher |
ELSEVIER
|
Date of Issued | 2018-01 |
Access Rights | metadata only access |
Relation |
[DOI] 10.1016/j.ebiom.2017.11.029
[PMID] 29254681
|
Remark | This work was supported by the Funding Program for the Next Generation of World-Leading Researchers (NEXT Program) from the Ministry of Education, Culture, Sports, Science and Technology of Japan to Y.A. (LS004), the Grants-in-Aid by the Practical Research Project for Rare/Intractable Diseases from the Japan Agency for Medical Research and Development, AMED to Y.A. (16eK0109021,17894363), by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Number 26293241 and 16K15522 to Y.A., and by JSPS KAKENHI Grant Number 15K19598 to S.I. |