Excessive Extracellular ATP Desensitizes P2Y2 and P2X4 ATP Receptors Provoking Surfactant Impairment Ending in Ventilation-Induced Lung Injury

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume 19 Issue 4 published_at 2018-04
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Title
Excessive Extracellular ATP Desensitizes P2Y2 and P2X4 ATP Receptors Provoking Surfactant Impairment Ending in Ventilation-Induced Lung Injury
Creator
Hasan Djo
Satalin Joshua
van der Zee Philip
Kollisch-Singule Michaela
Blankman Paul
Shono Atsuko
Somhorst Peter
den Uil Corstiaan
Meeder Han
Kotani Toru
Nieman Gary F.
Source Title
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19
Issue 4
Journal Identifire
ISSN 1422-0067
Subjects
extracellular ATP; purinergic signaling; P2X receptors; P2Y receptors; surfactant dysfunction; ventilation-induced lung injury; innate immunity ( Other)
Language
eng
Resource Type journal article
Publisher
MDPI
Date of Issued 2018-04
Access Rights metadata only access
Relation
[DOI] 10.3390/ijms19041185
[PMID] 29652806
Remark Djo Hasan: The author reports to have received an honorarium to a lecture from Demcon-Macawi; Michaela Kollisch-Singule: The author reports to have received travel reimbursement at events sponsored by Drager Medical; Gary F. Nieman.: The author reports to have received grants from the NIH, a grant from Drager Medical, a grant from the CDRMP (DoD), travel and honorarium to lecture from Drager Medical; Joshua Satalin, Philip van der Zee, Paul Blankman, Atsuko Shono, Peter Somhorst, Corstiaan den Uil, Han Meeder and Toru Kotani: The authors declare no conflicts of interest.