Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin

SCIENTIFIC REPORTS Volume 8 published_at 2018-07-27
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Title
Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin
Creator
Ogawa Yuji
Imajo Kento
Honda Yasushi
Kessoku Takaomi
Tomeno Wataru
Kato Shingo
Fujita Koji
Yoneda Masato
Saito Satoru
Saigusa Yusuke
Hyogo Hideyuki
Sumida Yoshio
Itoh Yoshito
Eguchi Kosei
Yamanaka Takeharu
Nakajima Atsushi
Source Title
SCIENTIFIC REPORTS
Volume 8
Journal Identifire
ISSN 2045-2322
Language
eng
Resource Type journal article
Publisher
NATURE PUBLISHING GROUP
Date of Issued 2018-07-27
Access Rights metadata only access
Relation
[DOI] 10.1038/s41598-018-29735-6
[PMID] 30054551
Remark The skillful technical assistance of Machiko Hiraga and Ayaka Miura is gratefully acknowledged. This study was supported by the Japan Society for the Promotion of Science KAKENHI grant numbers 25860551 and 15K19340, and research grants from the Liver Forum in Kyoto. We thank Lynley Pound, Ph.D., from Edanz Group (www.edanzediting.com/ac) for editing a draft of this manuscript.