Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Volume 20 Issue 10 published_at 2019-05-2
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Title
Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway
Creator
Takeno Ayumu
Kanazawa Ippei
Source Title
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20
Issue 10
Journal Identifire
EISSN 1422-0067
Subjects
phloretin; bone marrow stromal cell; ST2 cell; osteoblast; MC3T3-E1 cell; glucose uptake; osteoblastogenesis; adipogenesis; PI3K; Akt pathway ( Other)
Language
eng
Resource Type journal article
Publisher
MDPI
Date of Issued 2019-05-2
Access Rights metadata only access
Relation
[DOI] 10.3390/ijms20102481
[PMID] 31137461
Remark This study was partly supported by a research grant from Eli Lilly Japan.