Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs

GENES Volume 11 Issue 2 published_at 2020-02
アクセス数 : 898
ダウンロード数 : 0

今月のアクセス数 : 0
今月のダウンロード数 : 0
Title
Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs
Creator
Srivastava Swayam Prakash
Goodwin Julie E.
Koya Daisuke
Source Title
GENES
Volume 11
Issue 2
Journal Identifire
EISSN 2073-4425
Subjects
diabetic nephropathy; ACE; ARBs; AcSDKP; DPP-4; EMT; EndMT; kidney fibrosis
Language
eng
Resource Type journal article
Publisher
MDPI
Date of Issued 2020-02
Access Rights metadata only access
Relation
[DOI] 10.3390/genes11020211
[PMID] 32085655
Remark This work was partially supported by grants from the Japan Society for the Promotion of Science for M Kitada (24591218), TN (24659264), KK (23790381), DK (25282028, 25670414, and research grants from the Japan Research Foundation for Clinical Pharmacology to K.K. (2011), and Takeda visionally research grant to K.K. (2013). This work was partially supported by a Grant for Collaborative Research awarded to DK (C2011-4, C2012-1) and a Grant for Promoted Research awarded to KK (S2011-1, S2012-5) from Kanazawa Medical University. KK was also supported by several foundational grants, including grants from the Japan Research Foundation for Clinical Pharmacology, the Daiichi-Sankyo Foundation of Life Science, the Ono Medical Research Foundation, the NOVARTIS Foundation (Japan) for the Promotion of Science, the Takeda Science Foundation, and the Banyu Foundation. KK and DK received lecture fees from Both Boehringer Ingelheim, Eli Lilly, and Mitsubishi Tanabe Pharma. Boehringer Ingelheim, Eli Lilly, and Mitsubishi Tanabe Pharma donated to Kanazawa Medical University and were not directly associated with this project. JG is supported by a grant from the National Institutes of Health (R01HL131952).