Semicircle flap reconstruction and immunohistochemical study in squamous cell carcinoma of the upper eyelid

Abstract

A 52-year-old woman complained of recurrent upper eyelid mass in her left eye. The lesion was excised under the histopathological diagnosis of squamous cell carcinoma. Although it involved 67% of the length of the upper eyelid margin, we could encompass the defect using a Tenzel semicircle rotation flap. The functional result was excellent. This technique may be useful in the repair of defects involving up to two-thirds of the upper eyelid margin. Strong immunostaining for proliferating cell nuclear antigen, Ki-67,epidermal growth factor receptor and c-erb B-2 was demonstrated in this tumor.