Dose Response Curves of Althesin on Spontaneous Single Unit Activity of Various Dorsal Horn Rexed Laminae

Shimane journal of medical science Volume 5 Issue 1 Page 31-36 published_at 1981-06-01
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Title
Dose Response Curves of Althesin on Spontaneous Single Unit Activity of Various Dorsal Horn Rexed Laminae
Creator
Yoshikawa Osami
Kosaka Yoshihiro
Takahashi Takeo
Source Title
Shimane journal of medical science
Volume 5
Issue 1
Start Page 31
End Page 36
Journal Identifire
ISSN 03865959
Descriptions
Dose response curves of Althesin on single unit activities of various dorsal horn Rexed laminae were studied using an extracellular microelectrode recording technique in decerebrated spinal cats. Althesin 33,50,100 and 200μl/kg I. V. suppressed in a dose related manner spontaneous single unit activity in Rexed lamina 5,known to respond principally to noxious stimuli. Althesin 100μl/kg and 200μl/kg depressed in a dose related manner spontaneous single unit activity in a lamina 4 and lamina 6,but a small dose of Althesin 33μl/kg and 50μl/kg I. V. did not suppress lamina 4 and lamina 6,with proprioceptive input, rather these units were adversely facilitated.
Subjects
spinal cord ( Other)
Althesin ( Other)
anesthesia ( Other)
Language
eng
Resource Type departmental bulletin paper
Date of Issued 1981-06-01
Publish Type Version of Record
Access Rights open access
Relation
[NCID] AA00841586