ファイル
言語
英語
属性
テクニカルノート
著者
山本 泰司 放射線部
西山 祐一 放射線医学講座
原元 益夫 放射線部
Sota, Takumi 島根県立中央病院
宮井 將宏 放射線部
内部 拓 放射線部
矢田 伸広 放射線部
西山 由佳子 放射線部
北垣 一 放射線医学講座
内容記述(抄録等)
This study examined the utility of cadmium-zinctelluride (CZT) semiconductor camera for quantifying striatal tracer uptake in single-photon emission computed tomography (SPECT) with 123I-ioflupane (DaTSCAN). An anthropomorphic striatal phantom was prepared with 123I-ioflupane. The phantom images were obtained using a CZT camera and a traditional Anger-type camera for 5 min and 30 min, respectively. Phantom image quality was visually evaluated, and the contrast between the striatal and cerebral parenchyma (background region) was examined via count profile analysis. Then, the specific binding ratio (SBR), which indicates 123I uptake in the striatum, was measured. There were no visual differences in striatal shape between the scans, but the CZT/SPECT scan exhibited better image contrast. The SBR obtained from the CZT/SPECT images were higher than those acquired from the Anger/SPECT images and were closer to the true values. Performing CZT/SPECT using DaTSCAN might enable more accurate evaluations of striatal function while reducing the imaging time.
主題
dopamine transporter
single-photon emission computed tomography
cadmium zinc telluride
phantom study
掲載誌名
Shimane Journal of Medical Science
34
1
開始ページ
35
終了ページ
40
ISSN
03865959
ISSN(Online)
24332410
発行日
2017-07-31
NCID
AA00841586
出版者
Faculty of Medicine, Shimane University
出版者別表記
島根大学医学部
資料タイプ
紀要論文
ファイル形式
PDF
権利関係
Faculty of Medicine, Shimane University
著者版/出版社版
出版社版
部局
医学部