ダウンロード数 : ?
ファイル
言語
英語
属性
Original article
著者
江角 知香
内容記述(抄録等)
P57 is known to have anti-tumor activity through inhibition of cyclin-dependent kinases. We performed immunohistochemical analysis on expression of P57 in 92 cases of epithelial ovarian carcinoma (EOC), of which, 31, 14, 18 and 29 were diagnosed as serous, mucinous, endometrioid (EC) and clear cell carcinoma (CCC), respectively. Of 92 cases of EOC, 6 and 28 were positive for P57 in the nucleus and the cytoplasm, respectively. Five cases of 29 CCC (17.2%) were positive in the nucleus, which was significantly greater than in non-CCC (p = 0.03). In contrast, positive cases in the cytoplasm were significantly greater in EC (55.6 and 23.0% for EC and non-EC, respectively, p = 0.01). Expression patterns of nuclear and cytoplasmic p57 showed no correlations with clinical stage of EOC. Clinicopathological significance of P57 expression in EOC would need further investigation.
主題
epithelial ovarian carcinoma
p57
immunohistochemistry
clear cell carcinoma
endometrioid carcinoma
掲載誌名
Shimane Journal of Medical Science
39
1
開始ページ
33
終了ページ
39
ISSN
03865959
ISSN(Online)
24332410
発行日
2022-03
NCID
AA00841586
DOI
出版者
Faculty of Medicine, Shimane University
出版者別表記
島根大学医学部
資料タイプ
紀要論文
ファイル形式
PDF
権利関係
Faculty of Medicine, Shimane University
権利関係(リンク)
著者版/出版社版
出版社版
部局
医学部
他の一覧