生活習慣と認知症: 食事と運動による認知症予防

The prevention of dementia is a growing public health concern.　Epidemiological data indicate a protective role of certain micronutrients（ the anti-oxidant vitamins C and E, flavonoids, ω-3 fatty acids, vitamin D） and exercise in the agerelated cognitive decline and dementia.　However, many of the results obtained by interventions tested in randomized control trials（ RCTs） are conflicting with observational evidence.　This paper is outlined the relevance of cognitive function, micronutrients and exercise, and after that review the possibility of preventive effects of ω-3 fatty acids, especially docosahexaenoic acid, in the prevention of dementia.