ダウンロード数 : ?
ファイル
言語
英語
属性
原著論文
著者
Takahashi, Satoru
Kawabe, Tetsuya
Murakami, Masao
楫 靖
Nakazawa, Masanori
Fukazawa, Kazuo
Sekihara, Kazumasa
内容記述(抄録等)
We used the accelerated hyperfractionated radiotherapy of locally advanced cervical cancer and assessed the initial treatment efficacy and safety.
This study enrolled three patients. Using a field-infield technique, the whole pelvic region was set as a large irradiated field and received a dose of 35.2-39.6 Gy, whereas small field irradiation targeting only the tumor and parametrium was performed at
9.6-10.8 Gy. We then performed center shield field irradiation of the pelvic lymph node area, which were irradiated at 50 Gy in sum total. Intracavitary radiotherapy was added two to three times. Two patients received chemotherapy. In all patients, treatments
were completed with overall treatment time (OTT) of 37-40 days. All patients were in complete response. Acute adverse events included two cases of grade 3 leukopenia, one case of grade 3 neutropenia.
In conclusion, this treatment was effective and safet with good outcomes, acceptable adverse events, and greatly reduced OTT.
主題
cervical cancer
hyperfractionated radiotherapy
safety
efficacy
accelerated repopulation
掲載誌名
Shimane journal of medical science
30
2
開始ページ
77
終了ページ
86
ISSN
03865959
ISSN(Online)
24332410
発行日
2014-01-01
NCID
AA00841586
出版者
Shimane University Faculty of Medicine
資料タイプ
紀要論文
ファイル形式
PDF
著者版/出版社版
出版社版
業績ID
e27129
部局
医学部
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