| 言語 |
英語
|
| 著者 |
Van Roon Anne-Marie M.
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
Oubridge Chris
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
Sposito Benedetta
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
Newman Andrew J.
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
Seraphin Bertrand
Equipe Labellisée La Ligue, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Centre National de la Recherche Scientifique (CNRS) UMR 7104/Institut National de la Santé et de la Recherche Médicale (INSERM), U964/Université de Strasbourg, 67404 Illkirch, France
Nagai Kiyoshi
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
|
| 主題 | splicing; U2 snRNP; SF3b; RNA binding; RRM
|
| 掲載誌名 |
RNA
|
| 巻 | 23
|
| 号 | 6
|
| 開始ページ | 968
|
| 終了ページ | 981
|
| ISSN | 1355-8382
|
| ISSN（Online） | 1469-9001
|
| 発行日 | 2017-06
|
| DOI | |
| PubMed ID | |
| 出版者 | COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
|
| 資料タイプ |
学術雑誌論文
|
| 部局 |
医学部
|
| 備考 | We thank Yasushi Kondo for collecting data on the RRM1-Cusl (290-368)p complex crystals and LMB mass spectrometry facility for MALDI-TOF analysis of proteolytic fragments, Dr. Stephen McLaughlin for helping with fluorescence anisotropy data analysis, and the staff at Diamond Light Source beamline 102 and European Synchrotron Radiation Facility beamline ID14-3 for their assistance. We also thank Elena Conti and Sebastian Falk for communicating their unpublished results. We are grateful to Lisa Strittmatter and Pei-chun Lin for critical reading of the manuscript. This project was supported by the Medical Research Council (MC_U105184330), a Wellcome Trust Travelling fellowship, and an MRC career development fellowship (E.O.). B.Sp. was supported by Humanitas Research Foundation. B.Se. was supported by the CNRS, the CERBM-IGBMC and INSERM, the grant ANR-10LABX-0030-INRT, a French State fund managed by the Agence Nationale de la Recherche under the frame program Investissements d'Avenir ANR-10-IDEX-0002-02, and the Ligue Contre le Cancer (Equipe Labellisee 2014).
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