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ファイル
言語
英語
日本語以外のタイトル
Visualization of decreased docosahexaenoic acid in the hippocampus of rats fed an n-3 fatty acid-deficient diet by imaging mass spectrometry.
著者
Taira, Shu Japan Advanced Institute of Science and Technology, Ishikawa, Japan
橋本 道男
Saito, Kazunori Bruker Daltonics K.K., Kanagawa, Japan
内容記述(抄録等)
The present study employed an imaging mass spectrometry (IMS) method to evaluate the effect of dietary n – 3 fatty acids on the fatty acid composition in rat brain. Rats were divided into two groups and fed either an n – 3 fatty acid-deficient or adequate diet. We determined the decreased n – 3 fatty acids in the hippocampus of rats fed an n – 3 fatty acid-deficient diet compared to the control. IMS visualization was achieved at a resolution of 100 m in rat brain, and showed decreased docosahexaenoic acid (DHA)-containing phosphatidyl choline (PC) or phosphatidyl ethanolamine (PE) in the hippocampus of rats fed an n – 3 fatty acid-deficient diet.
主題
Docosahexaenoic Acid
Imaging Mass Spectrometry
Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry
Hippocampus
掲載誌名
Journal of Biophysical Chemistry
3
3
開始ページ
221
終了ページ
226
発行日
2012-8
DOI
出版者
Scientific Research Publishing Inc.
資料タイプ
学術雑誌論文
著者版/出版社版
出版社版
業績ID
e14599
部局
医学部
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