Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(冊子体)
ISSN :2433-2410(オンライン)

クリエイティブ・コモンズ・ライセンス
これらの論文は クリエイティブ・コモンズ 表示 - 非営利 - 改変禁止 4.0 国際 ライセンスの下に提供されています。
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Shimane Journal of Medical Science 4 1
1980-06-01 発行

Studies of Administration of Disodium-α-Sulfobenzyl-penicillin under Surgical Conditions of Extracorporeal Circulation

山田 公弥
龍田 憲和
大頭 信義
松田 光彦
Kisaki, Yoshihiko
日笠 頼則
岡本 好史
中瀬 明
ファイル
内容記述(抄録等)
Administration of antibiotics in cases of open heart surgery under conditions of extracorporeal circulation requires careful management with regard to prophylaxis against infection as well as possible renal failure.In this study, the dose of semi-synthetic penicillin SB-PC was calculated from the sum of the assessed circulating blood volume, based on body weight and the priming volume. As a result of a study on the concentration in the circulating blood, the antibiotics was administered via drip infusion, at a constant rate throughout the operation, under extracorporeal circulation, in order to obtain a stable concentration.