Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(冊子体)
ISSN :2433-2410(オンライン)

クリエイティブ・コモンズ・ライセンス
これらの論文は クリエイティブ・コモンズ 表示 - 非営利 - 改変禁止 4.0 国際 ライセンスの下に提供されています。
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Shimane Journal of Medical Science 24
2007-12-01 発行

Anti-glomerular basement membrane antibody associated with human parvovirus B19 infection

Horie, Akiyoshi
四本 由郁
山口 清次
ファイル
内容記述(抄録等)
An eleven years old girl developed glomerulone-phritis, showing positive antibody against glomerular basement membrane (anti-GBM) associated with acute human parvovirus B19 (HPVB19) infection. She was admitted with fever, rash, and joint pain.
Additionally, hematuria, proteinuria, and hypocomple-mentemia were present. HPVB19 DNA and anti-GBM antibody were positive in blood. A kidney biopsy showed mesangial proliferative glomerulone-phritis. Subsequently, steroid pulse therapy was given, followed by oral prednisolone and cyclophosphamide, After the steroid pulse therapy, the urinary findings improved, and anti-aBM antibody became undetectable, also the glomerulonephritis has not recurred. The HPVB19 infection appeared to have induced the production of anti-GBM antibody in this patient.