Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5

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言語	英語
著者	尾林栄治 Luna Rafael E. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Nagata Takashi Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan Martin-Marcos Pilar Laboratory of Gene Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA Hiraishi Hiroyuki Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Singh Chingakham Ranjit Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Erzberger Jan Peter Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland Zhang Fan Laboratory of Gene Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA Arthanari Haribabu Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Morris Jacob Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Pellarin Riccardo California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA Moore Chelsea Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Harmon Ian Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Papadopoulos Evangelos Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Yoshida Hisashi Graduate School of Medical Life Science, Yokohama City University, Tsurumi-ku, Yokohama 230-0045, Japan / Drug Design Group, Kanagawa Academy of Science and Technology, Takatsu-ku, Kawasaki 213-0012, Japan Nasr Mahmoud L. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Unzai Satoru Graduate School of Medical Life Science, Yokohama City University, Tsurumi-ku, Yokohama 230-0045, Japan Thompson Brytteny Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Aube Eric Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Hustak Samantha Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Stengel Florian Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland Dagraca Eddie Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Ananbandam Asokan COBRE-PSF, University of Kansas, Lawrence, KS 66047, USA Gao Philip COBRE-PSF, University of Kansas, Lawrence, KS 66047, USA 浦野健 Hinnebusch Alan G. Laboratory of Gene Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA Wagner Gerhard Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Asano Katsura Molecular Cellular Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, KS 66506, USA
掲載誌名	CELL REPORTS
巻	18
号	11
開始ページ	2651
ISSN	2211-1247
発行日	2017-03-14
DOI	10.1016/j.celrep.2017.02.052
PubMed ID	28297669
出版者	CELL PRESS
資料タイプ	学術雑誌論文
部局	医学部
備考	We thank Hiroshi Matsuo and Erin Adamson for comments, Ivan Topisirovic for proofreading, and Michaela Flax and Speed Rogers for technical assistance. This work was supported by a grant from the NIH (R01 GM64781), a pilot grant from University of Kansas COBRE-PSF (P30 GM 110761), and an Innovative Award from KSU Terry Johnson Cancer Center to K.A.; CA68262 and GM47467 to G.W.; an intramural grant from NICHD, NIH, to A.G.H.; and JSPS KAKENHI 15H01634 and 26440026 to T.N.