Specific mtDNA Mutations in Mouse Carcinoma Cells Suppress Their Tumor Formation via Activation of the Host Innate Immune System

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言語	英語
著者	Imanishi Hirotake Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan, Japan Society for the Promotion of Science, Tokyo, Japan, Department of Molecular Immunology and Inflammation, National Center for Global Health and Medicine, Tokyo, Japan Takibuchi Gaku Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan Kobayashi Toshihiko Department of Molecular Immunology and Inflammation, National Center for Global Health and Medicine, Tokyo, Japan Ishikawa Kaori Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan Nakada Kazuto Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan, International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan Mori Masayuki Department of Aging Angiology, Research Center on Aging and Adaptation, Shinshu University School of Medicine, Matsumoto, Nagano, Japan Kikkawa Yoshiaki Mammalian Genetics Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan 竹永啓三 Toyama-Sorimachi Noriko Department of Molecular Immunology and Inflammation, National Center for Global Health and Medicine, Tokyo, Japan Hayashi Jun-Ichi Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan, International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
掲載誌名	PLOS ONE
巻	8
号	9
ISSN	1932-6203
発行日	2013-09-30
DOI	10.1371/journal.pone.0075981
PubMed ID	24098752
出版者	PUBLIC LIBRARY SCIENCE
資料タイプ	学術雑誌論文
部局	医学部
備考	This work was supported by Grants-in-Aid for Scientific Research A 25250011 (to JIH), Scientific Research A 23240058 (to KN), and Scientific Research on Innovative Areas 24117503 (to JIH) from Japan Society for the Promotion of Science (JSPS). This work was also supported by Grant-in-Aid for JSPS Fellows (to HI) and by World Premier International Research Center Initiative, Ministry of Education, Culture, Sports, Science, and Technology, Japan (to KN and JIH). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscripts.