ダウンロード数 : ?
ファイル
言語
英語
著者
Demizu, Ryuta Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu,Matsue 690-8504, Japan
Ohkado, Ryoma Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu,Matsue 690-8504, Japan
内容記述(抄録等)
A green, aerobic sulfenylation of imidazo[ 1,2-a]pyridines was performed using thiols, a flavinand- iodine dual catalytic system, and environmentally benign molecular oxygen as the only sacrificial reagent. The dual metal-free catalysts smoothly promote a unique stepwise tandem process, beginning with the aerobic oxidation of a thiol to afford a disulfide that is utilized in the oxidative sulfenylation of the imidazo[1,2-a]pyridine. This process has afforded diverse 3-sulfenylimidazo[1,2-a]pyridines of biological interest, and is environmentally friendly as benign H2O is the only by-product.
主題
Disulfides
Reagents
Flavins
Thiols
Catalysts
掲載誌名
The Journal of Organic Chemistry
83
19
開始ページ
12291
終了ページ
12296
ISSN
0022-3263
ISSN(Online)
1520-6904
発行日
2018-10-1
DOI
出版者
American Chemical Society
資料タイプ
学術雑誌論文
ファイル形式
PDF
権利関係
https://s100.copyright.com/AppDispatchServlet?startPage=12291&pageCount=6&copyright=American+Chemical+Society&author=Hiroki+Iida%2C+Ryuta+Demizu%2C+Ryoma+Ohkado&orderBeanReset=true&imprint=American+Chemical+Society&volumeNum=83&issueNum=19&contentID=acs.joc.8b01878&title=Tandem+Flavin-Iodine-Catalyzed+Aerobic+Oxidative+Sulfenylation+of+Imidazo%5B1%2C2-a%5DPyridines+with+Thiols&numPages=6&pa=&issn=0022-3263&publisherName=acs&publication=joceah&rpt=n&endPage=12296&publicationDate=October+2018
著者版/出版社版
著者版
業績ID
e34995
部局
総合理工学部
備考
J. Org. Chem. 2018, 83, 19, 12291-12296