Intratumoral Genomic Heterogeneity May Hinder Precision Medicine Strategies in Patients with Serous Ovarian Carcinoma

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言語	英語
著者	Nakamura, Kohei 1 Genomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan 2 Department of Obstetrics and Gynecology, Kumagaya General Hospital, Saitama 360-8657, Japan Aimono, Eriko Genomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan Tanishima, Shigeki Department of Biomedical Informatics, Kansai Division, Mitsubishi Space Software Co., Ltd, Tokyo 661-0001, Japan Imai, Mitsuho Genomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan Kawano Nagatsuma, Akiko Genomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan Hayashi, Hideyuki Genomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan Yoshimura, Yuki Department of Obstetrics and Gynecology, Shimane University School of Medicine, Enyacho 89-1, Izumo 693-8501, Japan 中山健太郎京哲 Nishihara, Hiroshi Genomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan
主題	ovarian carcinoma; genomic heterogeneity; precision medicine; DNA sequencing
掲載誌名	DIAGNOSTICS
巻	10
号	4
ISSN（Online）	2075-4418
発行日	2020-04
DOI	10.3390/diagnostics10040200
PubMed ID	32260152
出版者	MDPI
資料タイプ	学術雑誌論文
部局	医学部
備考	This study was supported by the JSPS KAKENHI (Grant-in-Aid for Young Scientists B) Grant Number 20K18232, and the Japan Agency for Medical Research and Development (AMED) under grant number JP 16kk0205006.