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言語
英語
著者
Nogi, Akiko Department of Environmental and Preventive Medicine, Shimane University School of Medicine Department of Human Nutrition, Faculty of Human Life Science, Yamaguchi Prefectural University
Yang, Jianjun Department of Environmental and Preventive Medicine, Shimane University School of Medicine
Li, Limei Department of Environmental and Preventive Medicine, Shimane University School of Medicine
Watanabe, Minako Department of Environmental and Preventive Medicine, Shimane University School of Medicine
橋本 道男
塩飽 邦憲
内容記述(抄録等)
The favorable role of n-3 polyunsaturated fatty acid (PUFA) in cardiovascular disease (CVD) has been demonstrated in animal experiments and in humans in Western countries, but its effect remains controversial in Asian populations. An observational study of Japanese, Koreans and Mongolians with extended histories of remarkably different frequencies of fish intake was conducted to examine whether differences in plasma n-3 PUFA affects CVD risk factors. We conducted a cross-sectional study in workplace settings and determined body mass index (BMI), blood pressure, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride (TG), glucose, insulin, homeostasis model assessment-insulin resistance (HOMA-IR) and fatty acid composition in plasma. A total of 411 Japanese, 418 Korean and 252 Mongolian workers aged 30-60 yr participated in this study. The Japanese ate fish more frequently and had remarkably higher values of eicosapentaenoic acid, docosahexaenoic acid and n-3 PUFA, and lower values of BMI and HOMA-IR, followed by the Koreans, and then the Mongolians. In age groups, the Japanese and Koreans showed a similar tendency of increase in n-3 PUFA with increasing age. General linear measurement multivariate analysis after adjustment for gender, age, smoking, drinking, exercise habits and BMI showed n-3 PUFA was associated with HDL-C and TG in the Japanese, while it was associated with systolic blood pressure in the Koreans, and TG in the Mongolians. In conclusion, an increase in n-3 PUFA was associated with HDL-C and TG in the Japanese and Mongolians, but these beneficial effects were not constant across the three Asian ethnic groups.
主題
n-3 PUFA
fish
triglyceride
HDL-cholesterol
insulin resistance
Asian
掲載誌名
Journal of Occupational Health
49
3
開始ページ
205
終了ページ
216
並び順
205
ISSN
1341-9145
ISSN(Online)
1348-9585
発行日
2007
DOI
出版者
公益社団法人 日本産業衛生学会
出版者ヨミ
コウエキ シャダン ホウジン ニホン サンギョウ エイセイ ガッカイ
出版者別表記
Japan Society for Occupational Health
資料タイプ
学術雑誌論文
SUタイプ
9001
関連情報
業績ID
e16799
部局
医学部
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