ダウンロード数 : ?
ファイル
言語
英語
著者
石川 典由 医学部
Nagano, Nahoko Tenosynovial Giant Cell Tumor, Localized Type With Extensive Chondroid Metaplasia: A Case Report With Immunohistochemical and Molecular Genetic Analysis
Fujimoto, Makiko Shimane University, Izumo, Shimane, Japan
Biyajima Kyoko Shimane University, Izumo, Shimane, Japan
内容記述(抄録等)
Tenosynovial giant cell tumor (TSGCT) of localized type is a common disease occurring mostly in the hands. Diagnosis of this tumor is relatively easy to render with hematoxylin-eosin–stained sections as compared with that of TSGCT of diffuse type. However, very rare cases with chondroid metaplasia that have recently been reported mainly in diffuse type can make pathological differentiation from soft tissue cartilaginous tumors extremely difficult. In this article, the authors present the second reported case of TSGCT of localized type showing extensive chondroid metaplasia. Pathological interpretation was difficult without utilizing immunohistochemistry and fluorescence in situ hybridization. One must be careful not to misdiagnose this lesion as cartilaginous tumors of soft tissue, and we suspect at least some chondroblastoma-like chondroma could be reclassified as TSGCT of localized type with extensive chondroid metaplasia. Morphological, immunohistochemical, and molecular genetic characteristics are presented and discussed.
主題
tenosynovial giant cell tumor
localized type
chondroid metaplasia, clusterin
COL6A3-CSF1 fusion gene
掲載誌名
International Journal of Surgical Pathology
28
4
開始ページ
447
終了ページ
453
ISSN
1066-8969
ISSN(Online)
1940-2465
発行日
2019-11-26
DOI
PubMed ID
出版者
SAGE
資料タイプ
学術雑誌論文
ファイル形式
PDF
関連情報
著者版/出版社版
著者版
部局
医学部
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