| ファイル | |
| 言語 |
英語
|
| 著者 |
Demizu, Ryuta
Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu,Matsue 690-8504, Japan
Ohkado, Ryoma
Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu,Matsue 690-8504, Japan
|
| 内容記述（抄録等） | A green, aerobic sulfenylation of imidazo[ 1,2-a]pyridines was performed using thiols, a flavinand- iodine dual catalytic system, and environmentally benign molecular oxygen as the only sacrificial reagent. The dual metal-free catalysts smoothly promote a unique stepwise tandem process, beginning with the aerobic oxidation of a thiol to afford a disulfide that is utilized in the oxidative sulfenylation of the imidazo[1,2-a]pyridine. This process has afforded diverse 3-sulfenylimidazo[1,2-a]pyridines of biological interest, and is environmentally friendly as benign H2O is the only by-product.
|
| 主題 | Disulfides
Reagents
Flavins
Thiols
Catalysts
|
| 掲載誌名 |
The Journal of Organic Chemistry
|
| 巻 | 83
|
| 号 | 19
|
| 開始ページ | 12291
|
| 終了ページ | 12296
|
| ISSN | 0022-3263
|
| ISSN（Online） | 1520-6904
|
| 発行日 | 2018-10-1
|
| DOI | |
| 出版者 | American Chemical Society
|
| 資料タイプ |
学術雑誌論文
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| ファイル形式 |
PDF
|
| 権利関係 | https://s100.copyright.com/AppDispatchServlet?startPage=12291&pageCount=6©right=American+Chemical+Society&author=Hiroki+Iida%2C+Ryuta+Demizu%2C+Ryoma+Ohkado&orderBeanReset=true&imprint=American+Chemical+Society&volumeNum=83&issueNum=19&contentID=acs.joc.8b01878&title=Tandem+Flavin-Iodine-Catalyzed+Aerobic+Oxidative+Sulfenylation+of+Imidazo%5B1%2C2-a%5DPyridines+with+Thiols&numPages=6&pa=&issn=0022-3263&publisherName=acs&publication=joceah&rpt=n&endPage=12296&publicationDate=October+2018
|
| 著者版/出版社版 |
著者版
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| 業績ID | e34995
|
| 部局 |
総合理工学部
|
| 備考 | J. Org. Chem. 2018, 83, 19, 12291-12296
|
