Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism

ダウンロード数 : ? 件

この文献の参照には次のURLをご利用ください : https://ir.lib.shimane-u.ac.jp/55216

言語	英語
著者	Uehara, Shotaro Liver Engineering Laboratory, Department of Applied Research for Laboratory Animals, Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan. 飯田雄一 Ida-Tanaka, Miyuki Liver Engineering Laboratory, Department of Applied Research for Laboratory Animals, Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan. Goto, Motohito Animal Resource and Technical Research Center, CIEA, Kawasaki, Japan. Kawai, Kenji Pathological Analysis Center, CIEA, Kawasaki, Japan. Yamamoto, Masafumi ICLAS Monitoring Center, CIEA, Kawasaki, Japan. Higuchi , Yuichiro Liver Engineering Laboratory, Department of Applied Research for Laboratory Animals, Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan. Ito, Satoshi Drug Development Solutions Center, Sekisui Medical Co., Ltd., Ibaraki, Japan. Takahashi, Riichi Animal Resource and Technical Research Center, CIEA, Kawasaki, Japan. Kamimura , Hidetaka Drug Development Solutions Center, Sekisui Medical Co., Ltd., Ibaraki, Japan.　/　Laboratory Animal Research Department, CIEA, Kawasaki, Japan. Ito Mamoru Liver Engineering Laboratory, Department of Applied Research for Laboratory Animals, Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan. Yamazaki , Hiroshi Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan. Oshimura, Mitsuo Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Japan. Kazuki, Yasuhiro Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Japan./Department of Chromosome Biomedical Engineering, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan. Suemizu, Hiroshi Liver Engineering Laboratory, Department of Applied Research for Laboratory Animals, Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan. suemizu@ciea.or.jp.
掲載誌名	Scientific Reports
巻	12
号	1
ISSN（Online）	2045-2322
発行日	2022-09-01
DOI	10.1038/s41598-022-19242-0
PubMed ID	36050438
出版者	Springer Nature
資料タイプ	学術雑誌論文
権利関係（リンク）	This work is licensed under CC BY 4.0
業績ID	e42903
部局	生物資源科学部