ダウンロード数 : ?
ファイル
言語
英語
著者
Gamoh, Shuji
橋本 道男
Yanagimoto, Kenichi
片倉 賢紀
Haque Md Abdul
内容記述(抄録等)
We indicated previously that dietary supplementation of the ethyl ester form of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) improves spatial cognition through an increase in DHA levels in the hippocampus and cerebral cortex. In the present study, we investigated the effects of peroral administration of krill-derived phospholipids (KPL) on the spatial learning ability and the fatty acid composition of the plasma and brain tissues. Both parameters of the radial arm maze task, the reference- and working memory errors, significantly decreased after KPL administration. The plasma and brain levels of n-3 PUFAs significantly increased, and the levels of arachidonic acid were significantly decreased after KPL administration. Lipid peroxidation in the plasma and in brain tissues was depressed, and cell generation in the dentate gyrus was enhanced in KPL-administered rats. All these effects are similar to those induced by the ethyl ester forms of EPA and DHA.
掲載誌名
Journal of Agricultural Science
3
4
ISSN
1916-9752
ISSN(Online)
1916-9760
DOI
出版者
The Canadian Center of Science and Education
資料タイプ
学術雑誌論文
ファイル形式
PDF
著者版/出版社版
出版社版
業績ID
e13260
部局
医学部
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