Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner

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言語	英語
著者	Sumi Chisato Department of Anesthesiology, Kansai Medical University, Hirakata, Japan, Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Okamoto Akihisa Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Tanaka Hiromasa Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Nishi Kenichiro Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Kusunoki Munenori Department of Anesthesiology, Kansai Medical University, Hirakata, Japan, Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Shoji Tomohiro Department of Anesthesiology, Kansai Medical University, Hirakata, Japan, Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Uba Takeo Department of Anesthesiology, Kansai Medical University, Hirakata, Japan, Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Matsuo Yoshiyuki Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan Adachi Takehiko Department of Anesthesiology, Tazuke Kofukai Medical Institute Kitano Hospital, Osaka, Japan Hayashi Jun-Ichi University of Tsukuba, Tsukuba, Japan Takenaga Keizo Department of Life Science, Shimane University Faculty of Medicine, Izumo, Japan Hirota Kiichi Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan
掲載誌名	PLOS ONE
巻	13
号	2
ISSN	1932-6203
発行日	2018-02-15
DOI	10.1371/journal.pone.0192796
PubMed ID	29447230
出版者	PUBLIC LIBRARY SCIENCE
資料タイプ	学術雑誌論文
部局	医学部
備考	This work was supported by the Japan Society for the Promotion of Science KAKENHI, Grants #26670693 and #24592336 to K.H., #25462457 to K.N., and #15K15577 to T.A., and by a research grant from Katano Kai to K.H. and A.O. This work was supported by the research grant B from Kansai Medical University to A.O., the KMU consortium grant from Kansai Medical University to K.H. and the research grant from Katano Kai to A.O. and K.H. This work was supported by the Japanese Society of Anesthesiologists (JSA) Pitch Contest 2017 to C.S. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.