ファイル | |
言語 |
英語
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著者 |
Tamura-Nakano, Miwa
Nakaya, Fumio
飯田 智宏
Iwata, Yoko
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内容記述(抄録等) | Spermatozoa released by males should remain viable until fertilization. Hence, sperm longevity is governed by intrinsic and environmental factors in accordance with the male mating strategy. However, whether intraspecific variation of insemination modes can impact sperm longevity remains to be elucidated. In the squid Heterololigo bleekeri, male dimorphism (consort and sneaker) is linked to two discontinuous insemination modes that differ in place and time. Notably, only sneaker male spermatozoa inseminated long before egg spawning can be stored in the seminal receptacle. We found that sneaker spermatozoa exhibited greater persistence in fertilization competence and flagellar motility than consort ones because of a larger amount of flagellar glycogen. Sneaker spermatozoa also showed higher capacities in glucose uptake and lactate efflux. Lactic acidosis was considered to stabilize CO2-triggered self-clustering of sneaker spermatozoa, thus establishing hypoxia-induced metabolic changes and sperm survival. These results, together with comparative omics analyses, suggest that postcopulatory reproductive contexts define sperm longevity by modulating the inherent energy levels and metabolic pathways.
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掲載誌名 |
Journal of biological chemistry
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巻 | 291
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号 | 37
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開始ページ | 19324
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終了ページ | 19334
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ISSN | 00219258
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発行日 | 2016-09-09
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DOI | |
DOI公開日 | 2016-12-14
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PubMed ID | |
NCID | AA00251083
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出版者 | American Society for Biochemistry and Molecular Biology
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資料タイプ |
学術雑誌論文
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ファイル形式 |
PDF
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権利関係 | This research was originally published in 'Journal of biological chemistry'. Noritaka Hirohashi, Miwa Tamura-Nakano, Fumio Nakaya, Tomohiro Iida and Yoko Iwata. Sneaker Male Squid Produce Long-lived Spermatozoa by Modulating Their Energy Metabolism. Journal of biological chemistry. 2016; 291:19324-19334. © the American Society for Biochemistry and Molecular Biology
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著者版/出版社版 |
著者版
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部局 |
生物資源科学部 附属生物資源教育研究センター
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