Janus kinase inhibition for autoinflammation in patients with DNASE2 deficiency

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言語	英語
著者	Hong Ying University College London Great Ormond Street Institute of Child Health, London, United Kingdom Capitani Melania Translational Gastroenterology Unit, Department of Pediatrics, and Oxford Biomedical Research Centre (BRC), University of Oxford, Oxford, United Kingdom Murphy Claire University College London Great Ormond Street Institute of Child Health, London, United Kingdom　/　Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Pandey Sumeet Translational Gastroenterology Unit, Department of Pediatrics, and Oxford Biomedical Research Centre (BRC), University of Oxford, Oxford, United Kingdom Cavounidis Athena Translational Gastroenterology Unit, Department of Pediatrics, and Oxford Biomedical Research Centre (BRC), University of Oxford, Oxford, United Kingdom 竹下治男 Nanthapisal Sira University College London Great Ormond Street Institute of Child Health, London, United Kingdom　/　Thammasat University, Bangkok, Thailand Yasuda, Toshihiro Department of Medical Genetics and Biochemistry, University of Fukui, Fukui, Japan Bader-Meunier Brigitte Department of Pediatric Immunology and Rheumatology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France McCreary Dara University College London Great Ormond Street Institute of Child Health, London, United Kingdom Omoyinmi Ebun University College London Great Ormond Street Institute of Child Health, London, United Kingdom Rao Anupama Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Booth Claire University College London Great Ormond Street Institute of Child Health, London, United Kingdom　/　Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Gilmour Kimberly Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Sebire Neil Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Shah Neil Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Klein Nigel University College London Great Ormond Street Institute of Child Health, London, United Kingdom　/　Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Bullock Alex N. Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom Eleftheriou Despina University College London Great Ormond Street Institute of Child Health, London, United Kingdom　/　Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom Uhlig Holm H. Translational Gastroenterology Unit, Department of Pediatrics, and Oxford Biomedical Research Centre (BRC), University of Oxford, Oxford, United Kingdom Brogan Paul University College London Great Ormond Street Institute of Child Health, London, United Kingdom　/　Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom
掲載誌名	JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
巻	145
号	2
開始ページ	701
終了ページ	+
ISSN	0091-6749
ISSN（Online）	1097-6825
発行日	2020-02
DOI	10.1016/j.jaci.2019.11.020
PubMed ID	31775019
出版者	MOSBY-ELSEVIER
資料タイプ	学術雑誌論文
部局	医学部
備考	This work was funded in part by Rosetrees, Great Ormond Street Hospital Children's Charity, and Versus Arthritis (grants 21791, 21593 and 21064). All research at the Great Ormond Street Hospital National Health Service (NHS) Foundation Trust and UCL Great Ormond Street Institute of Child Health is made possible by the National Institute of Health Research (NIHR)'s Great Ormond Street Hospital Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health. We acknowledge support for set-up of pilot experiments by the VBRC to the Oxford GI biobank (11/YH/0020 and 16/YH/0247). The research was also supported by the NIHR Oxford Biomedical Research Centre (BRC), University of Oxford, Wellcome Trust (grant 106169/ZZ14/Z), and the Structural Genomics Consortium SGC. H.H.U. is supported by NIHR Oxford BRC and the Leona M. and Harry B. Helmsley Charitable Trust.