ダウンロード数 : ?
ファイル
言語
英語
属性
Case Report
著者
KAJI, Sarasa
OHKURA, Takahiro
MURPHY, Lynne
内容記述(抄録等)
Ewing sarcoma (ES) is a high-grade malignancy usually identified in children and adolescents. Primary extraskeletal lesions of ES are rarely detected and no established treatments are available for advanced ES. A fifteen-year-old female presented with abdomen discomfort, and had high titer of neuron specific enolase (NSE), a specific tumor marker for neuroendocrine tumors. Radiological findings showed a large kidney mass with many nodules in bilateral lung and ilium. She was diagnosed as ES after total nephrectomy. She received chemotherapy and autologous peripheral blood stem cell transplantation accompanied with high-dose chemotherapy, but the tumor recurred in lung and bone. Our case suggests that it is necessary to differentiate ES for childhood and adolescent patients of large renal tumor with metastasis having high value of NSE. Developing a new treatment including molecular targeted therapy is warranted for patients with advanced ES.
主題
Ewing sarcoma
kidney
extraskeletal
EWS-FLI-1
NSE
掲載誌名
Shimane Journal of Medical Science
38
4
開始ページ
131
終了ページ
137
ISSN
03865959
ISSN(Online)
24332410
発行日
2021-12
NCID
AA00841586
DOI
DOI(SelfDOI)
出版者
Faculty of Medicine, Shimane University
出版者別表記
島根大学医学部
資料タイプ
紀要論文
ファイル形式
PDF
権利関係
Faculty of Medicine, Shimane University
権利関係(リンク)
著者版/出版社版
出版社版
部局
医学部
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