Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(冊子体)
ISSN :2433-2410(オンライン)

クリエイティブ・コモンズ・ライセンス
これらの論文は クリエイティブ・コモンズ 表示 - 非営利 - 改変禁止 4.0 国際 ライセンスの下に提供されています。
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Shimane Journal of Medical Science 3 1
1979-06-01 発行

Two Primary Melanomas of the Human Brain

猪俣 賢一郎
Izumi, Kazuo
Hirabayashi, Kazuaki
Oyama, Mitsuru
Tokito, Sumitaka
Ogawa, Kazuo
ファイル
内容記述(抄録等)
A malignant melanoma and a melanin-pigmented tumor, both showing spontaneous intracerebral hemorrhage, were reported. A definite diagnosis of melanoma was made almost exclusively by histological examination of tumor tissue obtained at operation or autopsy. A search for primary tumor foci was performed in both cases before and after death. No extracerebral melanomas were found.Thus, these cases can safely be regarded as primary cerebral tumors.
In the present paper two assumptions were made. One assumption concerning spontaneous intracerebral hemorrhage from melanomas is that tumor cells release a chemical factor which causes the formation of fenestrate and subsequent hemorrhage. Another assumption concerning malignant changes of melanoma cells is that malignant change is influenced by genetic factors.