Hodgkin's Disease in the Nose

We report herein a very rare case of Hodgkin's disease which developed in the right nasal region and followed a peculiar clinical course. A 56 year old Japanese woman complained of right nasal obstruction and bleeding. The lesion first showed evidence of nasal polyp and progressed slowly, but became aggravated and advanced rapidly immediately before admission. The clinical staging on admission was established as stage II_EA. The histologic type changed from one of mixed cellularity at onset of the treatment to the lymphocytic depletion type as seen at autopsy.