An epidemiological study has been done yearly in Daiwa Village, Shimane Prefecture, since 1978. In the survey, the serum uric acid (SUA) levels were measured and the distribution was examined. The SUA levels were related to sex and age. Normal subjects were seen in 520 of 571 males (91.1%) and 629 of 669 females (94%). In normal males, the mean SUA level was 5.2mg/dl (standard deviation; SD±1.1mg/dl, while in the females, the mean was 3.7mg/dl (±0.8mg/dl). The values were always lower than that in males, with a significant difference. In the male, under 30 and their 30s, the level of SUA were significantly higher than seen in other decades. The levels of SUA of females gradually decreased and then increased and the values in those over 70 years of age were higher than in the other decades. The results seen in females are similar to the previous findings, but the level of SUA in each decade in the males differed somewhat from previous data.