We report 2 cases of Harada's syndrome found to be difficult to diagnose in the initial stage.
In one patient, there was an elevation of intraocular pressure accompanied by a shallow anterior chamber depth in the very early phase of Harada's syndrome, preceding the appearance of fundic abnormality and the onset of iridocyclitis.
The shallow depth was considered to be caused by a forward movement of the lens due to ciliary changes and in this case mydriatic and steroid treatment gradully led to a normalization of the anterior chamber depth.
She had been treated with a miotic agent under the diagnosis of primary angle-closure glaucoma. This seems to have resulted from delayed detection of fundic abnormalities at the initial stage of onset and which induced a seclusion of the pupil.
　In the other patient, only papilledema of optic disc was remarkably evident in initial stage. The oscllatory potential in ERG decreased but A and B waves were fairly normal.
These findings suggested the importance of differentiation between optic neuritis and brain tumor.