Phototropin-Inspired Chemoselective Synthesis of Unsymmetrical Disulfides: Aerobic Oxidative Heterocoupling of Thiols Using Flavin Photocatalysis

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ID	53852
File	Phototropin-Inspired Chemoselective Synthesis of Unsymmetrical Disulfides: Aerobic Oxidative Heterocoupling of Thiols Using Flavin Photocatalysis 934 KB
language	eng
Author	Oka, Marina Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu, Matsue, 690-8504 Japan Katsube, Daichi Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu, Matsue, 690-8504 Japan TSUJI, Takeshi Iida, Hiroki
Description	Inspired by the photochemical mechanism of a plant blue-light receptor, a unique flavin-based photocatalytic system was developed for the chemoselective heterocoupling of two different thiols, which enabled the facile synthesis of unsymmetrical disulfides. Owing to the redox- and photo-organocatalysis of flavin, the coupling reaction took place under mild metal-free conditions and visible light irradiation with the use of air, which is recognized as the ideal green oxidant.
Subject	Disulfides Flavins Thiols,Adducts Heterocouplings
Journal Title	Organic Letters
Volume	22
Issue	23
Start Page	9244
End Page	9248
ISSN	1523-7060
Published Date	2020-12-04
DOI	10.1021/acs.orglett.0c03458
Publisher	American Chemical Society
NII Type	Journal Article
Format	PDF
Text Version	著者版
Gyoseki ID	38961
OAI-PMH Set	Faculty of Science and Engineering