ファイル
言語
英語
著者
橋本 道男
Haque, Abdul Md.
Sugioka, Kozo
片倉 賢紀
内容記述(抄録等)
Twenty-two 5-week-old male Wistar rats fed an n-3 fatty acid-adequate diet were supplemented with docosahexaenoic acid (DHA) administered perorally for 14 weeks. Six weeks after the start of the administralion, the rats were for 5 weeks trained to acquire a reward at the end of each of 4 arms of an 8-arm radial maze. The retention test interposed with a delayed task (20-min interval after acquiring the first 2 rewards) was then given to each rat to determine spatial working memory retention DHA administration reduced the number of working memory errors after the 20-min interval in the retention test and tended to induce an increase in the DHA/arachidonic acid ratio in the hippocampus, indicating that chronic administration of DHA to rats fed an n-3 fatty acid-adequate diet is conducive to the improvement of working memory-related learning abiiity.
掲載誌名
Shimane journal of medical science
22
2
開始ページ
29
終了ページ
34
ISSN
03865959
ISSN(Online)
24332410
発行日
2005-12-01
NCID
AA00841586
出版者別表記
Shimane University Faculty of Medicine
資料タイプ
紀要論文
ファイル形式
PDF
著者版/出版社版
出版社版
部局
医学部
備考
http://ci.nii.ac.jp/vol_issue/nels/AA00841586_jp.html