ダウンロード数 : ?
言語
英語
著者
Imanishi, Yasuo
Kitazawa, Riko
成相 義樹
Kobayashi, Keisuke
Inaba, Masaaki
山口 徹
内容記述(抄録等)
Malignant transformation of fibrous dysplasia is very rare and has not been previously described in patients with McCune-Albright syndrome in the absence of radiation treatment during gestation. Here, we report a 38-year-old pregnant woman with McCune-Albright syndrome and acromegaly accompanied by osteosarcoma. The patient was in the 6th week of pregnancy, when she visited our hospital. She had multiple fibrous dysplasia, skin pigmentation, and acromegaly. The markedly high bone turnover rate during pregnancy tended to decrease after a normal delivery. Fibrous dysplasia of the lower jaw rapidly increased in the 37th week of pregnancy, and the tumor was surgically resected after delivery. Pathological examination of the resected tumor revealed fibrous dysplasia admixed with osteosarcoma containing chondroblastic and osteoblastic tissue. We firstly reported a case of osteosarcoma in a patient with McCune-Albright syndrome, which rapidly progressed during pregnancy.
掲載誌名
Bone
45
3
開始ページ
603
終了ページ
608
ISSN
8756-3282
ISSN(Online)
1873-2763
発行日
2009-5-28
DOI
PubMed ID
出版者
New York : Elsevier Science
資料タイプ
学術雑誌論文
ファイル形式
PDF
著者版/出版社版
出版社版
業績ID
e9783
部局
医学部