ダウンロード数 : ?
ファイル
言語
英語
著者
Zhang, Hao
Ma, Lang
Hatta, Toshihisa
内容記述(抄録等)
The temporal profile of fetal-maternal adrenocortical activities, including blood corticosterone concentration and adrenal expression of cytochrome P45011ß, approaching parturition was investigated in mice. The fetal serum corticosterone concentration reached a peak on gestational day (G) 17 and maternal serum corticosterone reached a highest value on G15 and then subsequently decreased. Fetal and maternal adrenal expression of cytochrome P45011ß increased with advancing pregnancy before the blood corticosterone concentrations reached each peak but then did not change substantially until the term. The results suggest that the increases of blood fetalmaternal corticosterone concentrations before peak are contributed by the increased adrenocortical activities, whereas the subsequent drops after peaks are not adrenocortical dependent. Other possible factors responsible for the drop such as placental catabolism, tissue utilization and liver metabolism are discussed.
掲載誌名
Shimane journal of medical science
18
1
開始ページ
5
終了ページ
9
ISSN
03865959
ISSN(Online)
24332410
発行日
2000-06-01
NCID
AA00841586
出版者別表記
Shimane Medical University
資料タイプ
紀要論文
ファイル形式
PDF
著者版/出版社版
出版社版
部局
医学部
備考
http://ci.nii.ac.jp/vol_issue/nels/AA00841586_jp.html
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