ダウンロード数 : ?
ファイル
言語
英語
著者
橋本 道男
Kato, Setsushi Kato Hospital, Jinjukai Healthcare Corporation, Kawamoto, Shimane 696-0001, Japan.
Shahdat Hossain
Ohno, Miho Kato Hospital, Jinjukai Healthcare Corporation, Kawamoto, Shimane 696-0001, Japan.
内容記述(抄録等)
Perilla oil (PO), rich in α-linolenic acid (LNA, C18:3, ω-3), is increasingly alleged to have numerous health benefits in humans. However, the current reports detailing the effects of PO on human mental health are not adequate. Therefore, in the current investigation we compared the effects of PO or placebo treatment on the mental condition of healthy adult Japanese volunteers. At baseline and after 12 months of treatment, mental health condition was assessed using the Zung Self-Rating Depression Scale (SDS) and Apathy Scale, and serum biochemical parameters were determined. From baseline to 12 months of intervention, both SDS depression and apathy scores improved significantly in the PO-administered group. Compared to those of control group, serum norepinephrine and serotonin levels after 12 months decreased in the PO-administered group. The enhanced mental state observed in PO-subjects was accompanied by LNA level increases in erythrocyte plasma membranes. Our data demonstrate that PO intake enhances blood LNA levels and may maintain healthy mental conditions in adult subjects.
主題
apathy
depression
mental health
perilla oil
α-linolenic acid
ω-polyunsaturated fatty acid
掲載誌名
Foods
9
4
ISSN
2304-8158
DOI
PubMed ID
出版者
MDPI AG
資料タイプ
学術雑誌論文
ファイル形式
PDF
関連情報
著者版/出版社版
出版社版
部局
医学部
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