ダウンロード数 : ?
ファイル
言語
英語
属性
原著
著者
Yamaguchi, Shuhei
内容記述(抄録等)
Apathy is a quantitative reduction in goal-directed behaviors, having three subtypes. Despite executive deterioration in healthy aging, researchers have not investigated the “cognitive-deficit” subtype of apathy in healthy populations, which would result from executive dysfunction. We hypothesized that a relationship between apathy and executive function (EF) would be found in healthy older adults, accompanied with neural deterioration with functional dysconnectivity between the striatum and frontal region as suggested by previous studies. A total of 100 healthy adults in a health examination system database were analyzed. The present study indicates that apathy is substantially associated with executive deterioration, which can be partially ascribed to decreased functional connectivity between the frontal and ventral striatum. Despite some limitations, our findings may contribute to research on healthy psychological aging.
主題
age-related deterioration
executive function
cognitive apathy
neuroimaging
frontostriatal network
掲載誌名
Frontiers in Aging Neuroscience
9
発行日
2017-05-09
DOI
資料タイプ
学術雑誌論文
ファイル形式
PDF
著者版/出版社版
出版社版
部局
医学部
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