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language
eng
Author
Kobayashi, Yuta
Muramatsu, Ikunobu
Hidaka, Hiroyoshi
Fujiwara, Motohatsu
Description
Urophysial extracts (UE) of carp induced (1) dose-dependent vasopressor effect on the carp, Cyprinus carpio, (2) dose-dependent contraction of the helically cut strip of carp ventral aorta, which contraction was not mediated by the adrenergic or cholinergic system, and (3) a positive inotropic effect on the arterial strip of the carp. These results suggest that increase in blood pressure elicited by UE is at least partially mediated through the effects of UE on the contraction of the ventral aorta, probably on the contraction of the arterioles, and on the enhancement of the contractile force of beating on the atrium. Dose dependent contraction of the aortic strip was elicited by partially purified urotensins I (UI) and II (UII) as well as UE of the carp. The contraction of the aortic strip by UE was almost entirely due to UII contained in the UE.
Subject
caudal neurosecretory system
cardiovascular system
carp
Journal Title
Shimane journal of medical science
Volume
7
Issue
2
Start Page
57
End Page
66
ISSN
03865959
ISSN(Online)
24332410
Published Date
1983-12-01
NCID
AA00841586
Publisher Aalternative
Shimane Medical University
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
Gyoseki ID
e28118
OAI-PMH Set
Faculty of Medicine