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Title Transcription
3 デオキシグルコソン ニヨル メイラード ハンノウ ユライ ラジカル ノ ケンシュツ ト セイシツ
Title Alternative (English)
Detection and Characterization of Radicals Derived from 3-Deoxyglucosone in Maillard Reaction
File
language
jpn
Author
Kobayashi, Takayuki
Yasuda, Takayuki
Shibata, Hitoshi
Description
3-Deoxygluconsne(3-DG), an α, β-dicarbonyl compounds in phosphate buffer, pH7.4 with amino acids, produced different ESR spectra depending on the added amino acids, by the use of 3,5-dibromo-4-nitrosobenzenesulfonic acid(DBNBS)which is suitable for spin trapping of carbon centered radicals. 3-DG is known to polymerize protein, but added Lys promoted the dimerization of lysozyme by the involvement of radical generation. As the formation and accumulation of α, β-dicarbonyl compounds is known as carbonyl stress, we proposed that these radicals derived from amino acid via Maillard reaction may contribute oxidative stress, main part of carbonyl stress.
Journal Title
島根大学生物資源科学部研究報告
Volume
13
Start Page
19
End Page
23
ISSN
13433644
Published Date
2008-09-30
NCID
AA1112906X
Publisher
島根大学生物資源科学部
Publisher Aalternative
Shimane University, Faculty of Life and Environmental Science
NII Type
Departmental Bulletin Paper
OAI-PMH Set
Faculty of Life and Environmental Science
Remark
1-12+ / 1996-2007
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