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language
eng
Attribute
Case report
Author
Yamane, Yuko
Nishiki, Masateru
Kato, Yuzuru
Description
We report a 76-year-old man with type 2 diabetes mellitus (DM) complicated with diabetic nephropathy and lupus nephritis. The patient had a 7-year history of DM without renal dysfunction. He was referred to our hospital for severe arthralgia and right chest pain. Laboratory examination indicated urinary granular casts, but not proteinuria. Systemic lupus erythematosus (SLE) was suspected based on symptoms and further laboratory findings such as serum autoantibodies including anti-DNA antibody, antinuclear antibody and perinuclear anti-neutrophil cytoplasmic antibody. Finally, renal biopsy revealed mesangial sclerosis, subendothelial deposit of electron dense material and necrotic vasculitis, which were interpreted as diabetic nephropathy and lupus nephritis, respectively. Treatment with oral prednisolone ameliorated serological abnormalities as well as clinical symptoms. These findings indicate that renal biopsy is indispensable for a definite diagnosis of nephropathy in diabetic patients without proteinuria but with active urine sediments.
Journal Title
Shimane journal of medical science
Volume
19
Issue
2
Start Page
33
End Page
36
ISSN
03865959
ISSN(Online)
24332410
Published Date
2001-12-01
NCID
AA00841586
Publisher Aalternative
Shimane Medical University
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
Remark
http://ci.nii.ac.jp/vol_issue/nels/AA00841586_jp.html
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