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language
eng
Author
Kagohashi, Yukiko
Description
Nutrition has been suggested as an important environmental factor other than viruses and chemicals in the pathogenesis of type 1 diabetes (T1D). Whereas various maternal dietary nutritional elements have been suggested and examined in T1D of both humans and experimental animals, the results largely remain controversial. In a series of studies using T1D model nonobese diabetic (NOD) mice, maternal dietary n-6/n-3 essential fatty acid ratio during pregnancy and lactation period, that is, early life stages of the offspring, has been shown to affect pathogenesis of insulitis and strongly prevent overt T1D of the offspring, which is consistent with its preventive effects on other allergic diseases.
Journal Title
BioMed research international
Volume
2015
ISSN
2314-6133
ISSN(Online)
2314-6141
DOI
PubMed ID
Publisher
Hindawi Pub
NII Type
Journal Article
Format
PDF
Text Version
出版社版
Gyoseki ID
e28707
OAI-PMH Set
Faculty of Medicine