ダウンロード数 : ?
ファイル
言語
英語
著者
Fujiyoshi, Akira
Miura, Katsuyuki
Kadowaki, Sayaka
Azuma, Koichiro
Tanaka, Sachiko
久松 隆史
Arima, Hisatomi
Kadota, Aya
Miyagawa, Naoko
Takashima, Naoyuki
Ohkubo, Takayoshi
Saitoh, Yoshino
Torii, Sayuki
Miyazawa, Itsuko
Maegawa, Hiroshi
Murata, Kiyoshi
Ueshima, Hirotsugu
for the SESSA Research Group
内容記述(抄録等)
Studies from Western countries suggest that smokers tend to display greater abdominal obesity than non-smokers, despite showing lower weight. Whether this holds true in a leaner population requires clarification. Using indices of abdominal obesity including visceral adipose tissue, we examined whether lifetime cigarette smoking is associated with unfavorable fat distribution among Japanese men. From 2006 to 2008, we conducted a cross-sectional investigation of a community-based sample of Japanese men at 40-64 years old, free of cardiovascular diseases and cancer. Areas of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were calculated using computed tomography. We divided participants into four groups: never-smokers; and tertiles of pack-years of smoking among ever-smokers. Using multivariable linear regression, we calculated adjusted means of obesity indices (VAT, SAT, VAT-SAT ratio [VSR], and waist-hip ratio [WHR]) for each group, and mean differences between consecutive groups. We analyzed 513 men (median age, 58.2 years; current smokers, 40.1%). Two-thirds showed body mass index (BMI) < 25 kg/m(2) (median, 23.5 kg/m(2)). Overall, greater lifetime smoking group was associated with greater WHR and VSR. On average, one higher smoking group was associated with 0.005 higher WHR (95% CI, 0.001-0.008; P = 0.005) and 0.041 greater VSR (95% CI, 0.009-0.073; P = 0.012) after adjustment for potential confounders, including BMI. In this sample of relatively lean Japanese men, greater lifetime smoking was associated with a metabolically more adverse fat distribution. Although smoking is commonly associated with lower BMI, minimizing the amount of lifetime smoking should be advocated.
主題
Abdominal obesity
Smoking
Visceral adipose tissue
掲載誌名
Preventive medicine reports
4
開始ページ
225
終了ページ
232
ISSN
22113355
発行日
2016-06-16
DOI
PubMed ID
出版者
Elsevier
資料タイプ
学術雑誌論文
ファイル形式
PDF
権利関係
© 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
著者版/出版社版
出版社版
業績ID
e32258
部局
医学部