島根大学学術情報リポジトリ島根大学学術情報リポジトリ - 最新のデータ
http://ir.lib.shimane-u.ac.jp/ja/list/recent_addition
A new application method for nonoscillation criteria of Hille-Wintner type
http://ir.lib.shimane-u.ac.jp/38688
http://ir.lib.shimane-u.ac.jp/38688腹足類の這行運動に見る運動メカニズムと制御This study aim to investigate the mechanism of adhesive locomotion in gastropod. It has been reported by previous study that the significant factors of locomotion mechanism are “propagation of muscular waves” and “interfacial friction against the ground”. Interfacial friction has been considered to be controlled by lifting the pedal up, or dynamic viscoelasticity of mucus. To lift pedal up in appropriate timing, complex signals from the center would be necessary although the mechanism of lifting is simple in kinetics. This study focused on the hypothesis of dynamic viscoelasticity of mucus reported by Denny from the point of view of automatic frictional control similar to the mechanism of locomotion in earthworm. Based on the matter of previous study, a simple mathematical model which captures essential factors obtained by qualitative observations is proposed, and the physical parameters in the model are estimated by quantitative results from careful experiments. It has been verified by numerical calculations with the model that the mutual interaction between flexible muscular contraction waves and nonlinear dynamic viscoelasticity of the mucus can achieve an efficient locomotion. The important result in this study is that two locomotion styles, direct wave and retrograde wave, which has been understood by different mechanism, can be realized by the same mechanism.
http://ir.lib.shimane-u.ac.jp/39666
http://ir.lib.shimane-u.ac.jp/39666Geochemical examination of gold mining waste at Nzunguni in central TanzaniaWaste of gold mining at Nzunguni, central Tanzania was analyzed by X-ray fluorescence analysis (XRF) using the press powder method to evaluate environmental impact to the surrounding area. Gold (Aurum) occurred within quartz vein (reef) in the host granitic rock, which was separated by crushing the quartz vein and concentrated by gravity separation process on the slope. Mercury (Hg) was used for more concentration, but this process was not common in this site. Samples were collected at the gravity separation site, which were light yellowish gray silt. Aurum was detected in all 11 samples, even though only by qualitative analysis. This is because Au bearing standard powder was not obtained yet. Mercury was not detected for two samples which were treated with Hg at the site. Copper concentrations show variation from 500 to 1200 ppm suggesting relation of Au or Au bearing minerals. High Fe_2O_3 concentrations (10-19 wt%) in waste materials may be mainly derived from secondary formed iron oxide in cracks of quartz veins. Zn, Pb, Cr, Ni and V did not show high concentrations indicating absence of heavy minerals in the veins. Stream sediments did not show deviation of both Cu and Hg, suggesting negligible effects of contamination from the smelting process.
http://ir.lib.shimane-u.ac.jp/38868
http://ir.lib.shimane-u.ac.jp/38868Isolated Celiac Artery Dissection Caused by Segmental Arterial Mediolysis: A Case ReportWe encountered a case of intraabdominal hemorrhage caused by celiac artery dissection in a 74-year-old man. Angiography revealed the characteristic string-of-beads sign, irregular alternating arterial dilatations and stenoses giving a rosary-like appearance, which we suspected was caused by segmental arterial mediolysis （SAM） in the branches of the superior mesenteric artery （SMA）; these findings were observed in two locations along the pancreaticoduodenal artery and at one point along the small gastric branch. The patient was managed conservatively and the splanchnic arterial aneurysm believed to be the origin of the hemorrhage, as well as the aneurysm along the small gastric branch, resolved. There are no established criteria for invasive treatment of splanchnic artery aneurysms but this case suggests that thorough follow-up is necessary in cases of SAM.
http://ir.lib.shimane-u.ac.jp/40555
http://ir.lib.shimane-u.ac.jp/40555Improvement in the Quantification of Striatal Tracer Uptake in Single-photon Emission Computed Tomography With 123I-ioflupane Using a Cadmium-zinc-telluride Semiconductor CameraThis study examined the utility of cadmium-zinctelluride （CZT） semiconductor camera for quantifying striatal tracer uptake in single-photon emission computed tomography （SPECT） with 123I-ioflupane （DaTSCAN）. An anthropomorphic striatal phantom was prepared with 123I-ioflupane. The phantom images were obtained using a CZT camera and a traditional Anger-type camera for 5 min and 30 min, respectively. Phantom image quality was visually evaluated, and the contrast between the striatal and cerebral parenchyma （background region） was examined via count profile analysis. Then, the specific binding ratio （SBR）, which indicates 123I uptake in the striatum, was measured. There were no visual differences in striatal shape between the scans, but the CZT/SPECT scan exhibited better image contrast. The SBR obtained from the CZT/SPECT images were higher than those acquired from the Anger/SPECT images and were closer to the true values. Performing CZT/SPECT using DaTSCAN might enable more accurate evaluations of striatal function while reducing the imaging time.
http://ir.lib.shimane-u.ac.jp/40554
http://ir.lib.shimane-u.ac.jp/40554Diseases With Extremely Elevated Erythrocyte Sedimentation Rates in a Secondary Healthcare Facility: Retrospective Cohort StudyBackground: There is no data about the frequency of diseases with extremely elevated erythrocyte sedimentation rate （ESR） in secondary healthcare facilities in Japan.
Methods: We conducted a retrospective cohort study in Unnan City hospital in Shimane Prefecture to find out the frequency of diseases with ESR of more than 100 mm at one hour in a secondary healthcare facility in Japan. We gathered information on patients at the outpatient and emergency outpatient departments at the time of arrival and their final diagnosis.
Results: The total number of participants was 56, consisting of 19 men and 37 women. The average age recorded was 77.8 years. There were 30 cases （53.6%） of NIID（Non-infectious inflammatory disease）, 10 cases （17.9%） of infectious diseases, 10 cases （17.9%） of malignancy, 2 cases （3.6%） of other diagnoses, and 4 cases （7.1%） of unknown diagnoses. The most prevalent disease among patients with ESR of more than 100 mm at one hour was pseudogout.
Conclusion: There may be specific prevalence of the diseases with ESR of over 100 mm at one hour in rural hospitals. In diagnosing the patients showing extremely high ESR, It may be important to consider the possibility of the specific diseases in rural hospitals in Japan.
http://ir.lib.shimane-u.ac.jp/40553
http://ir.lib.shimane-u.ac.jp/40553Neuro-otological Examinations in Patients With Spinocerebellar DegenerationBackground: Spinocerebellar-degeneration （SCD） has been reported to show a variety of abnormal neurootological findings on electronystagmography （ENG） rather in a late stage of disease developing process, but not in an earlier stage.
Purpose: We have analysed ENG findings derived from 79 patients confirmed with SCD, in order to assess a diagnostic value of ENG and determine which manifestations are helpful in diagnosing SCD.
Results: We observed a high incidence of saccadic pursuit, severely impaired optokinetic nystagmus, and impaired visual suppression; observations that likely to be useful in diagnosing SCD. For each abnormal finding, we compared the data among patients with different types of SCD （olivopontocerebellar cortical atrophy, late cerebellar cortical atrophy, Shy-Drager syndrome, and hereditary SCD）. We also studied the relationship between MRI findings and ocular abnormalities in these patients with SCD. In typical cases, the abnormal neuro-otological findings are effective in an earlier diagnosis of SCD.
Conclusion: In our present study, neuro-otological examinations are demonstrated to be useful for evaluating patients with SCD.
http://ir.lib.shimane-u.ac.jp/40552
http://ir.lib.shimane-u.ac.jp/40552Comparative Analysis of the Prevalence of Congenital Heart Defects in the East Kazakhstan RegionAt present, the frequency and forms of congenital anomalies including malformations of the heart and blood vessels are poorly understood. More than 400 nuclear explosion tests were conducted at the Semipalatinsk Nuclear Test Site, and significant amounts of radioactive substances were released. In the present study, we researched inborn abnormalities in general and cardiovascular abnormalities in the Republic of Kazakhstan and administrative regions of the East Kazakhstan region among children using the official statistics data. Five years of data from the official statistics on the incidence of congenital abnormalities in the various regions of Kazakhstan were examined. We used indicators of congenital malformations （birth defects）, deformations and chromosomal abnormalities, and congenital defects of the heart and circulatory system in children aged 0 to 14 years. These anomalies are classified in InternationalStatistical Classification of Diseases and Related Health Problems 10th Revision （ICD-10） as the Q00-99, Q20-28. The average incidence, level of significance （p）, and 95% confidence interval were calculated for each area of the Republic of Kazakhstan and 19 settlements in the East Kazakhstan region. The results show a relatively high prevalence of congenital anomalies in the whole country and in the East Kazakhstan region.
http://ir.lib.shimane-u.ac.jp/40551
http://ir.lib.shimane-u.ac.jp/40551Effect of Surgical Instruments on Cytological Features: A Pilot Study of Mouse Tongue Cancer ModelsRapid intraoperative cytology is a common method for examining resection margins in cancer surgery. Cytopathologists often face challenges with cytological diagnoses because of cell degeneration by electric scalpels. This pilot study sought to elucidate the effect of surgical instruments on cytological features.
Mouse models of tongue SCC were used （n = 10）. Tumor was excised using a stainless-steel scalpel （n = 2, SS）, electronic scalpel （n = 2, ES）, or ultrasonic scalpel （n = 2, HS）. Imprint cytology specimens from resected tumor were subjected to Papanicolaou （Pap） or Giemsa staining. Remaining tissue was stained with hematoxylin and eosin. In SS specimens, heat-induced cell degeneration was observed less extensively than in ES. In perioperative rapid intraoperative cytology examination, surgeons should consider the possibility of changes in cellular morphology depending on the type of surgical instrument used. The cytopathologist should also be informed about the instrument used to resect the specimens.
http://ir.lib.shimane-u.ac.jp/40546
http://ir.lib.shimane-u.ac.jp/40546Parahyperbolic networksIn the study of potential theory on an infinite network X or an infinite tree T with terminal vertices, if the Laplacian is not defined at the terminal vertices considering them as boundary points of X, then X always has positive potentials and the constants are harmonic on X. Consequently, the harmonic classification theory of X has to be studied differently from an earlier study which treats T as a Brelot harmonic space.
http://ir.lib.shimane-u.ac.jp/7116
http://ir.lib.shimane-u.ac.jp/7116Flat parallel displacements and holonomy groups in a topological connection theoryIn a topological connection theory, we introduce the notion of flat for a parallel displacement and investigate holonomy groups of flat parallel displacements. Moreover, we assert a classicafication theorem in a category of principal bundles with flat parallel displacements, and give a sufficient condition for the existence of an initial object in the category.
http://ir.lib.shimane-u.ac.jp/28651
http://ir.lib.shimane-u.ac.jp/28651Non-locally-finite parahyperbolic networksIn the classification theory of Riemann surfaces the research for positive or bounded solutions of Δu = Pu, where P ＞__- 0 is a C^1－function, has played an important role in establishing the similarities between the solutions of this differential equation and the classical harmonic functions. In the discrete potential theory, the Schrödinger operators are to some extent like the equation Δu = Pu. In this note, we develop on an infinite graph, a theory of functions to reflect the properties of the above solutions, without the use of derivatives. This can be used to study discrete Schrödinger and Helmholtz equations in non-locally-finite networks.
http://ir.lib.shimane-u.ac.jp/28650
http://ir.lib.shimane-u.ac.jp/28650The dirichlet problem for ∞-harmonic functions on a networkWe define the notion of ∞-harmonic functions on a network as a discrete version of that on a euclidean domain, and show some properties of such functions. We discuss the Dirichlet problems for discrete ∞-harmonic functions. We also show that limits of discrete p-harmonic functions as p → ∞ are in factdiscrete ∞-harmonic.
http://ir.lib.shimane-u.ac.jp/28649
http://ir.lib.shimane-u.ac.jp/286491-harmonic functions on a networkA minimizer of the Dirichlet norm of order 1 is called a 1-harmonic function. The aim of this paper is a research of properties of 1-harmonic functions on a network. First we consider the 1-Dirichlet space and show that every network is of 1-hyperbolic type and that the ideal boundary coincides with the 1-harmonic boundary. Next we introduce the notion of 1-harmonic functions and that of strongly 1-harmonic functions. We discuss the Dirichlet problem and the maximum principle with respect to (strongly) 1-harmonic functions.
http://ir.lib.shimane-u.ac.jp/31493
http://ir.lib.shimane-u.ac.jp/31493Further bounds for Cebysev functional for power series in banach algebras via Grüss-Lupas type inequalities for p-normsSome Grüss-Lupas type inequalities for p-norms of sequences in Banach algebras are obtained. Moreover, if f(λ)=Σ^^∞__<n=0>α_nλ^n is a function defined by power series with complex coefficients and convergent on the open disk D(0,R)⊂C, R > 0 and x,y ∈ B, a Banach algebra, with xy = yx, then we also establish some new upper bounds for the norm of the Cebysev type difference
f(λ)f(λxy) - f(λx)f(λy), λ ∈ D(0,R).
These results build upon the earlier results obtained by the authors. Applications for some fundamental functions such as the exponential function and the resolvent function are provided as well.
http://ir.lib.shimane-u.ac.jp/34882
http://ir.lib.shimane-u.ac.jp/34882Quasi-bounded and singular functions in an infinite networkIn a hyperbolic network X, the properties of non-negative quasi-bounded harmonic functions and singular harmonic functions are considered by using the notion of reduced functions (balayage). Later some extensions of these results are given with respect to the class of non-negative quasi-bounded super-harmonic functions and the class of non-negative q-harmonic functions defined by discrete Schrödinger operators on X.
http://ir.lib.shimane-u.ac.jp/34881
http://ir.lib.shimane-u.ac.jp/34881Asymptotic theory for discriminant analysis in high dimension low sample sizeThis paper is based on the author's thesis, “Pattern recognition based on naive canonical correlations in high dimension low sample size”. This paper is concerned with discriminant analysis for multi-class problems in a High Dimension Low Sample Size (hdlss) context. The proposed discrimination method is based on canonical correlations between the predictors and response vector of class label. We investigate the asymptotic behavior of the discrimination method, and evaluate bounds for its misclassication rate.
http://ir.lib.shimane-u.ac.jp/31494
http://ir.lib.shimane-u.ac.jp/31494Symptotics for penalized splines in additive modelsThis paper is based on the author's thesis, Asymptotic theory of penalized spline regression. The focus of the present paper is on the penalized spline estimators obtained by the backfitting algorithm in additive models. The convergence of the algorithm as well as the uniqueness of its solution are shown. Asymptotic equivalence between the penalized spline estimators by the backfitting algorithm and the convenient estimators proposed by Marx and Eilers [9] is addressed. Asymptotic normality of the estimators is also developed.
http://ir.lib.shimane-u.ac.jp/28652
http://ir.lib.shimane-u.ac.jp/28652Kernel regression for binary response dataThis paper is based on the author's thesis, \Kernel Regression for Binary Response Data. We consider kernel-based estimators with additional weights of the regression functions in nonparametric binomial and binary regressions. Firstly, in the binomial regression with a single covariate and a xed covariate design, we introduce a weighted Nadaraya-Watson estimator and its bias adjusted estimator discussed in Okumura and Naito [13]. Secondly, in the binary regression with multiple covariates and a random covariate design, we propose weighted local linear estimators.
http://ir.lib.shimane-u.ac.jp/7119
http://ir.lib.shimane-u.ac.jp/7119Functional single nucleotide polymorphisms (SNPs) in the genes encoding the human deoxyribonulease (DNase) family potentially relevant to autoimmunityOBJECTIVE: To continue our previous investigations, we have extensively investigated the function of the 61, 41, and 35 non-synonymous single nucleotide polymorphisms (SNPs) in the human genes encoding DNASE1, DNASE1L3, and DNASE2, respectively, potentially relevant to autoimmune diseases.
METHODS: The site-directed mutagenesis was employed to amino acid-substituted constructs corresponding to each SNP. The COS-7 cells were transfected with each vector and DNase activity was assayed by the single radial enzyme diffusion method. By using PolyPhen-2, changes in the DNase function of each non-synonymous SNP were predicted. Genotyping of all the non-synonymous SNPs was performed in 14 different populations including 3 ethnic groups using the polymerase chain reaction followed by the restriction fragment length polymorphism method.
RESULTS: Expression analysis demonstrated these SNPs to be classified into four categories with regard to the effect on DNase activity: SNPs not affecting the activity level, ones reducing it, ones abolishing it, and ones elevating it. In particular, 9, 5, and 4 SNPs producing a loss-of-function variant of the enzymes in DNASE1, DNASE1L3, and DNASE2, respectively, were confirmed. SNPs producing DNase loss of function can be estimated by PolyPhen-2 to be "probably damaging" with a high accuracy of prediction. Almost all of these functional SNPs producing a loss of function or substantially low activity-harboring forms exhibited a mono-allelic distribution in all of the populations.
CONCLUSION: A minor allele of functional SNPs, despite the remarkably low genetic heterogeneity of the SNPs, might be a genetic risk factor for autoimmune diseases.
http://ir.lib.shimane-u.ac.jp/40158
http://ir.lib.shimane-u.ac.jp/40158