ファイル
言語
英語
属性
総説
著者
久松 隆史 環境保健医学講座
内容記述(抄録等)
Atherosclerotic cardiovascular disease (ASCVD),including coronary heart disease, remains a major cause of death and disability among developed countries. Coronary artery calcification (CAC), which is detected by computed tomography scanning, is a well-known measure of subclinical atherosclerosis. CAC is considered to have important implications for understanding the long-term accumulated burden of cardiovascular risk factors and for the possibility of reclassification at the preclinical phase for preventing ASCVD. This review focuses on CAC and its usability in primary prevention of ASCVD. Numerous epidemiological studies, mainly in Western countries, have indicated that, among asymptomatic individuals, the CAC score is associated with future ASCVD. Additionally, the CAC score provides improved predictive values for estimating the risk of ASCVD beyond traditional cardiovascular risk factors. However, a lack of evidence for this score in other populations warrants further investigations. Clinical trials are also necessary to demonstrate the usefulness and safety of CAC screening for primary prevention of ASCVD.
主題
atherosclerotic cardiovascular disease
coronary artery calcification
primary prevention
epidemiology
掲載誌名
Shimane Journal of Medical Science
34
1
開始ページ
1
終了ページ
5
ISSN
03865959
ISSN(Online)
24332410
発行日
2017-07-31
NCID
AA00841586
出版者
Faculty of Medicine, Shimane University
出版者別表記
島根大学医学部
資料タイプ
紀要論文
ファイル形式
PDF
権利関係
Faculty of Medicine, Shimane University
著者版/出版社版
出版社版
部局
医学部