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Original article
Author
Kotani, Satoshi Shimane Prefectural Central Hospital
Sato, Shiyuichi Department of Gastroenterology and Hepatology
Kohge, Naruaki Shimane Prefectural Central Hospital
Tsukano, Kosuke Shimane Prefectural Central Hospital
Ogawa, Sayaka Shimane Prefectural Central Hospital
Yamanouchi, Satoshi Shimane Prefectural Central Hospital
Kusunoki, Ryusaku Shimane Prefectural Central Hospital
Aimi, Masahito Shimane Prefectural Central Hospital
Miyaoka, Yoichi Shimane Prefectural Central Hospital
Fujishiro, Hirofumi Shimane Prefectural Central Hospital
Yamamoto, Tomohiko Shimane Prefectural Central Hospital
Ohnuma, Hideyuki Shimane Prefectural Central Hospital
Description
Objective: We aimed to evaluate the diagnostic accuracy
of shear wave elastography( SWE) for the assessment
of liver fibrosis in patients with liver disease.
Methods: A total of 54 consecutive patients who underwent
SWE measurement and liver biopsy were included.
Receiver-operator characteristic (ROC) curves
were constructed to calculate the area under the ROC
curve( AUC) for F0-2 versus F3-4 and F0-3 versus F4.
Results: Fibrosis scores estimated by SWE were F0 for
9 cases, F1 for 18 cases, F2 for 11 cases, F3 for 9 cases,
and F4 for 7 cases. AUCs for severe fibrosis (F3 and
F4) and cirrhosis (F4) were 0.931 (P < 0.001) and
0.916 (P < 0.001), respectively. Shear wave velocity
correlated significantly with liver fibrosis obtained by
liver biopsy( r = 0.679, P < 0.001).
Conclusion: SWE is a useful and non-invasive technology
to estimate liver fibrosis in liver disease regardless
of etiology.
Subject
chronic liver disease
liver fibrosis
shear wave elastographycoronary
Journal Title
Shimane Journal of Medical Science
Volume
34
Issue
2
Start Page
47
End Page
53
ISSN
03865959
ISSN(Online)
24332410
Published Date
2017-12-31
NCID
AA00841586
Publisher
Faculty of Medicine, Shimane University
Publisher Aalternative
島根大学医学部
NII Type
Departmental Bulletin Paper
Format
PDF
Rights
Faculty of Medicine, Shimane University
Text Version
出版社版
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Faculty of Medicine
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