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File
language
eng
Attribute
original article
Author
Takahashi, Satoru
Kawabe, Tetsuya
Murakami, Masao
Kaji, Yasushi
Nakazawa, Masanori
Fukazawa, Kazuo
Sekihara, Kazumasa
Description
We used the accelerated hyperfractionated radiotherapy of locally advanced cervical cancer and assessed the initial treatment efficacy and safety.
This study enrolled three patients. Using a field-infield technique, the whole pelvic region was set as a large irradiated field and received a dose of 35.2-39.6 Gy, whereas small field irradiation targeting only the tumor and parametrium was performed at
9.6-10.8 Gy. We then performed center shield field irradiation of the pelvic lymph node area, which were irradiated at 50 Gy in sum total. Intracavitary radiotherapy was added two to three times. Two patients received chemotherapy. In all patients, treatments
were completed with overall treatment time (OTT) of 37-40 days. All patients were in complete response. Acute adverse events included two cases of grade 3 leukopenia, one case of grade 3 neutropenia.
In conclusion, this treatment was effective and safet with good outcomes, acceptable adverse events, and greatly reduced OTT.
Subject
cervical cancer
hyperfractionated radiotherapy
safety
efficacy
accelerated repopulation
Journal Title
Shimane journal of medical science
Volume
30
Issue
2
Start Page
77
End Page
86
ISSN
03865959
ISSN(Online)
24332410
Published Date
2014-01-01
NCID
AA00841586
Publisher
Shimane University Faculty of Medicine
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
Gyoseki ID
e27129
OAI-PMH Set
Faculty of Medicine
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